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Kang, Byoung Heon (강병헌)

Department
School of Life Sciences(생명과학부)
Research Interests
Mitochondrial chaperones, cancer biology, cell death, metabolism, cancer stem cells, cancer therapeutics development
Lab
Cancer Biology Lab
Website
https://sites.google.com/site/mitomed/
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2020-03Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting DrugHu, Sung; Ferraro, Mariarosaria; Thomas, Ajesh P., et alARTICLE10 Dual Binding to Orthosteric and Allosteric Sites Enhances the Anticancer Activity of a TRAP1-Targeting Drug
2020-01Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1Jung, Sejin; Yoon, Nam Gu; Yang, Sujae, et alARTICLE59 Discovery of 2-((4-resorcinolyl)-5-aryl-1,2,3-triazol-1-yl)acetates as potent Hsp90 inhibitors with selectivity over TRAP1
2020-01Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1Park, Hye-Kyung; Yoon, Nam Gu; Lee, Ji-Eun, et alARTICLE55 Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1
2019-10Mitochondrial Heat Shock Protein-Guided Photodynamic TherapyThomas, Ajesh P.; Lee, An-Jung; Palanikumar, L, et alARTICLE141 Mitochondrial Heat Shock Protein-Guided Photodynamic Therapy
2019-04Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cellsPark, Hye-Kyung; Hong, Jun-Hee; Oh, Young Taek, et alARTICLE223 Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells
2018-04TRAP1 Inhibition Increases Glutamine Synthetase Activity in Glutamine Auxotrophic Non-small Cell Lung Cancer CellsVo, Vu T. A.; Choi, Jong-Whan; Phan, Ai N. H., et alARTICLE288 TRAP1 Inhibition Increases Glutamine Synthetase Activity in Glutamine Auxotrophic Non-small Cell Lung Cancer Cells
2017-09Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 InhibitorsPark, Hye-Kyung; Jeong, Hanbin; Ko, Eunhwa, et alARTICLE506 Paralog Specificity Determines Subcellular Distribution, Action Mechanism, and Anticancer Activity of TRAP1 Inhibitors
2017-08The novel resveratrol derivative 3,5-diethoxy-3', 4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitroPark, Jae-woo; Choi, Woo-gyun; Lee, Phil-jun, et alARTICLE450 The novel resveratrol derivative 3,5-diethoxy-3', 4'-dihydroxy-trans-stilbene induces mitochondrial ROS-mediated ER stress and cell death in human hepatoma cells in vitro
2015-04Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1Lee, Changwook; Park, Hye-Kyung; Jeong, Hanbin, et alARTICLE873 Development of a Mitochondria-Targeted Hsp90 Inhibitor Based on the Crystal Structures of Human TRAP1
2015-03장수풍뎅이 유충의 간보호 효능 및 항암활성Lee, Ji-Eun; Jo, Da-Eun; Lee, An-Jung, et alARTICLE1843 장수풍뎅이 유충의 간보호 효능 및 항암활성
2015-02Cytotoxic effects of Tenebrio molitor larval extracts against hepatocellular carcinomaLee, ji-Eun; Lee, An-Jung; Jo, Da-Eun, et alARTICLE1130 Cytotoxic effects of Tenebrio molitor larval extracts against hepatocellular carcinoma
2014-12Crystallization and preliminary X-ray diffraction analysis of Trap1 complexed with Hsp90 inhibitorsKang, Byoung Heon; Jeong, Hanbin; Lee, ChangwookARTICLE857 Crystallization and preliminary X-ray diffraction analysis of Trap1 complexed with Hsp90 inhibitors
2014-11Hepatoprotective and antineoplastic properties of Protaetia brevitarsis larvaeLee, Ji-Eun; Jo, Da-Eun; Lee, An-Jung, et alARTICLE568 Hepatoprotective and antineoplastic properties of Protaetia brevitarsis larvae
2014-07OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ miceYang, Yongryoul; Jang H.J.; Yoon, Sunyoung, et alARTICLE940 OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ mice
2014-06Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cellsPark, Hye-Kyung; Lee, Ji-Eun; Lim, Jaehwa, et alARTICLE635 Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells
2014-06Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of BimPark, Hye-Kyung; Lee, Ji-Eun; Lim, Jaehwa, et alARTICLE710 Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim
2012-06PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-beta 3 (PLC-beta 3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-beta 3 and Somatostatin ReceptorsKim, Jung Kuk; Kwon, Ohman; Kim, Jinho, et alARTICLE873 PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-beta 3 (PLC-beta 3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-beta 3 and Somatostatin Receptors
2012-01TRAP1 regulation of mitochondrial life or death decision in cancer cells and mitochondria-targeted TRAP1 inhibitorsKang, Byoung HeonARTICLE679 TRAP1 regulation of mitochondrial life or death decision in cancer cells and mitochondria-targeted TRAP1 inhibitors
2011-05Developmental Control of Apoptosis by the Immunophilin Aryl Hydrocarbon Receptor-interacting Protein (AIP) Involves Mitochondrial Import of the Survivin ProteinKang, Byoung Heon; Xia, Fang; Pop, Ramona, et alARTICLE594 Developmental Control of Apoptosis by the Immunophilin Aryl Hydrocarbon Receptor-interacting Protein (AIP) Involves Mitochondrial Import of the Survivin Protein
2011-02Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of diseaseKang, Byoung Heon; Tavecchio, M.; Goel, H. L., et alARTICLE609 Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease

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