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남덕우
Nam, Dougu

남덕우

Department of Biological Sciences(생명과학과)

Research Interests
Bioinformatics;Genomics;Systems biology;Single-cell data;Transcriptomics;GWAS;microRNA
Lab Description
We are bioinformatics group at UNIST.
Our research interests are as follows:(1) Identifying molecular markers and their functional networks that are associated with disease by analyzing transcriptomic and genomic data(2) Developing computational models and algorithms that impact bio-medical research(3) Classifying disease subtypes or cell types using gene expression big data (microarray, RNA-seq, single cell)
To this aim, we analyze microarrays, RNA-seq, GWAS, and single cell data in an integrative manner.We also use and develop machine learning methods for data processing, clustering, dimension reduction, and classification.
Current Topics of Interest:Development of single-cell data processing, clustering, and classification methodsBiclustering analysis of transcriptome big dataPathway and network analysis of gene expression and GWAS dataDetection of rare drivers in cancer by integrating mutation and expressionRead count modeling and simulation of RNA-seq and single cell dataImproving miRNA target prediction
Researcher ID Research Gate ORCiD Scopus Google Scholar
Previous
Impacts of the accumulated extinction of endangered species on stream food webs File File

Lee, Minyoung , Kim, Yongeun , Nam, Dougu , Cho, Kijong

Article Issue Date2023-12 View13
Benchmarking integration of single-cell differential expression File File

Nguyen, Hai C. T. , Baik, Bukyung , Yoon, Sora , Park, Taesung , Nam, Dougu

Article Issue Date2023-03 View9
MicroRNA-29 Ameliorates Fibro-Inflammation and Insulin Resistance in HIF1α-Deficient Obese Adipose Tissue by Inhibiting Endotrophin Generation File

Jo, Woobeen , Kim, Min , Oh, Jiyoung , Kim, Chu-Sook , Park, Chanho , Yoon, Sora , Lee, Changhu , Kim, Sahee , Nam, Dougu , Park, Jiyoung

Article Issue Date2022-08 View12
Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA File

Lee, Yo Han , Jang, Hyun-Jun , Kim, Sounkou , Choi, Sun Sil , Khim, Keon Woo , Eom, Hye-Jin , Hyun, Jimin , Shin, Kyeong Jin , Chae, Young Chan , Kim, Hongtae , et al

Article Issue Date2021-12 View16
Powerful p-value combination methods to detect incomplete association File File

Yoon, Sora , Baik, Bukyung , Park, Taesung , Nam, Dougu

Article Issue Date2021-03 View8
Diffusible Signaling Factor, a Quorum-Sensing Molecule, Interferes with and Is Toxic Towards Bdellovibrio bacteriovorus 109J File

Dwidar, Mohammed , Jang, Hyochan , Sangwan, Naseer , Mun, Wonsik , Im, Hansol , Yoon, Sora , Choi, Sooin , Nam, Dougu , Mitchell, Robert J.

Article Issue Date2021-02 View7
netGO: R-Shiny package for network-integrated pathway enrichment analysis File

Kim, Jinhwan , Yoon, Sora , Nam, Dougu

Article Issue Date2020-05 View12
Benchmarking RNA-seq differential expression analysis methods using spike-in and simulation data File File

Baik, Bukyung , Yoon, Sora , Nam, Dougu

Article Issue Date2020-04 View4
The voltage-gated potassium channel Shaker promotes sleep via thermosensitive GABA transmission File File

Kim, Ji-hyung , Ki, Yoonhee , Lee, Hoyeon , Hur, Moon Seong , Baik, Bukyung , Hur, Jin-Hoe , Nam, Dougu , Lim, Chunghun

Article Issue Date2020-04 View9
Bioinformatics services for analyzing massive genomic datasets File File

Ko, Gunhwan , Kim, Pan-Gyu , Cho, Youngbum , Jeong, Seongmun , Kim, Jae-Yoon , Kim, Kyoung Hyoun , Lee, Ho-Yeon , Han, Jiyeon , Yu, Namhee , Ham, Seokjin , et al

Article Issue Date2020-03 View7
Androgen-induced expression of DRP1 regulates mitochondrial metabolic reprogramming in prostate cancer File

Lee, Yu Geon , Nam, Yeji , Shin, Kyeong Jin , Yoon, Sora , Park, Weon Seo , Joung, Jae Young , Seo, Jeong Kon , Jang, Jinho , Lee, Semin , Nam, Dougu , et al

Article Issue Date2020-02 View10
PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273 File File

Khim, Keon Woo , Choi, Sun Sil , Jang, Hyun-Jun , Lee, Yo Han , Lee, Eujin , Hyun, Ji-Min , Eom, Hye-Jin , Yoon, Sora , Choi, Jeong-Won , Park, Tae-Eun , et al

Article Issue Date2020-02 View9
Glucosylceramide synthase regulates adipo‐osteogenic differentiation through synergistic activation of PPARγ with GlcCer File

Jang, Hyun-Jun , Lim, Seyoung , Kim, Jung-Min , Yoon, Sora , Lee, Chae Young , Hwang, Hyeon-Jeong , Shim, Jeong Woo , Shin, Kyeong Jin , Kim, Hye Yun , Park, Kwang Il , et al

Article Issue Date2020-01 View12
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 File File

Park, Hye-Kyung , Yoon, Nam Gu , Lee, Ji-Eun , Hu, Sung , Yoon, Sora , Kim, So Yeon , Hong, Jun-Hee , Nam, Dougu , Chae, Young Chan , Park, Jong Bae , et al

Article Issue Date2020-01 View12
Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury File File

Yoo, Eun Jin , Lim, Sun Woo , Kang, Hyun Je , Park, Hyun , Yoon, Sora , Nam, Dougu , Sanada, Satoru , Kwon, Mi Jin , Lee-Kwon, Whaseon , Choi, Soo Youn , et al

Article Issue Date2019-10 View13
GScluster: Network-weighted gene-set clustering analysis File File

Yoon, Sora , Kim, Jinhwan , Kim, Seon-Kyu , Baik, Bukyung , Chi, Sang-Mun , Kim, Seon-Young , Nam, Dougu

Article Issue Date2019-05 View12
Biclustering analysis of transcriptome big data identifies condition-specific microRNA targets File File

Yoon, Sora , Nguyen, HCT , Jo, Woobeen , Kim, Jinhwan , Chi, Sang-Mun , Park, Jiyoung , Kim, Seon-Young , Nam, Dougu

Article Issue Date2019-05 View3
The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasomemediated degradation of PPAR gamma File File

Lee, Jae Min , Choi, Sun Sil , Lee, Yo Han , Khim, Keon Woo , Yoon, Sora , Kim, Byung-Gyu , Nam, Dougu , Suh, Pann-Ghill , Myung, Kyungjae , Choi, Jang Hyun

Article Issue Date2018-10 View6
Efficient pathway enrichment and network analysis of GWAS summary data using GSA-SNP2 File File

Yoon, Sora , Nguyen, Hai C. T. , Yoo, Yun J , Kim, Jinhwan , Baik, Bukyung , Kim, Sounkou , Kim, Jin , Kim, Sangsoo , Nam, Dougu

Article Issue Date2018-06 View8
Analysis of triangular motifs in protein interaction networks and their implications to protein ages and cancer genes File

Jeon, Hyeonseong , Kim, Suh-Ryung , Nam, Dougu , Yoo, Yun Joo

Article Issue Date2017-12 View6
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