사진

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Choi, Jang Hyun (최장현)

Department
School of Life Sciences(생명과학부)
Research Interests
Diabetes, Metabolic Disorders, PPARg, Gene Regulation, Anti-Diabetic Drug
Lab
Lab of Diabetes and Metabolism (LDM)
Website
http://sites.google.com/site/diabetesandmetabolism/
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2008-09Potential Inhibition of PDK1/Akt Signaling by Phenothiazines Suppresses Cancer Cell Proliferation and SurvivalChoi, Jang Hyun; Yang, Yong Ryoul; Lee, Seul Ki, et alARTICLE575 Potential Inhibition of PDK1/Akt Signaling by Phenothiazines Suppresses Cancer Cell Proliferation and Survival
2008-01Cleavage of focal adhesion kinase is an early marker and modulator of oxidative stress-induced apoptosisMian, Md. Firoz; Kang, Changkeun; Lee, Seunghwan, et alARTICLE624 Cleavage of focal adhesion kinase is an early marker and modulator of oxidative stress-induced apoptosis
2008-01Phospholipase C-epsilon augments epidermal growth factor-dependent cell growth by inhibiting epidermal growth factor receptor down-regulationYun, Sanguk; Hong, Won-Pyo; Choi, Jang Hyun, et alARTICLE581 Phospholipase C-epsilon augments epidermal growth factor-dependent cell growth by inhibiting epidermal growth factor receptor down-regulation
2007-11HVEM signaling in monocytes is mediated by intracellular calcium mobilizationHeo, Sook-Kyoung; Yoon, Min-A; Lee, Sang-Chul, et alARTICLE599
2007-08Phospholipase C-gamma 1 potentiates integrin-dependent cell spreading and migration through Pyk2/paxillin activationChoi, Jang Hyun; Yang, Yong-Ryoul; Lee, Seul Ki, et alARTICLE620 Phospholipase C-gamma 1 potentiates integrin-dependent cell spreading and migration through Pyk2/paxillin activation
2007-04In vitro assay of neurofilament light chain self-assembly using truncated mutantsKim, Sung-Kuk; Cho, Sang-Min; Lee, In-Bum, et alARTICLE550 In vitro assay of neurofilament light chain self-assembly using truncated mutants
2007On/Off-regulation of phospholipase C-gamma 1-mediated signal transductionChoi, Jang Hyun; Ryu, Sung Ho; Suh, Pann-GhillARTICLE590 On/Off-regulation of phospholipase C-gamma 1-mediated signal transduction
2006-12Phospholipase C gamma 1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1BChoi, Jang Hyun; Kim, Hyeon Soo; Kim, Sun-Hee, et alARTICLE653 Phospholipase C gamma 1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B
2006-10Identification of a new functional target of haloperidol metabolite: implications for a receptor-independent role of 3-(4-fluorobenzoyl) propionic acidKim, Hyeon Soo; Song, Minseok; Yumkham, Sanatombi, et alARTICLE633 Identification of a new functional target of haloperidol metabolite: implications for a receptor-independent role of 3-(4-fluorobenzoyl) propionic acid
2006-09Serotonin stimulates GnRH secretion through the c-Src-PLC gamma 1 pathway in GT1-7 hypothalamic cellsKim, Hyeon Soo; Yumkham, Sanatombi; Choi, Jang Hyun, et alARTICLE549 Serotonin stimulates GnRH secretion through the c-Src-PLC gamma 1 pathway in GT1-7 hypothalamic cells
2006-08Haloperidol induces calcium ion influx via L-type calcium channels in hippocampal HN33 cells and renders the neurons more susceptible to oxidative stressKim, Hyeon Soo; Yumkham, Sanatombi; Choi, Jang Hyun, et alARTICLE670
2006-06Pleckstrin homology domain of phospholipase C-gamma 1 directly binds to 68-kDa neurofilament light chainKim, Sung-Kuk; Choi, Jang Hyun; Suh, Pann-Ghill, et alARTICLE569
2006-06Neurotensin enhances nitric oxide generation via the JAK2-STAT1 pathway in murine macrophage Raw264.7 cells during costimulation with LPS and IFN gammaKim, HS; YumkhaM, S; Choi, Jang Hyun, et alARTICLE575 Neurotensin enhances nitric oxide generation via the JAK2-STAT1 pathway in murine macrophage Raw264.7 cells during costimulation with LPS and IFN gamma
2005-10Grb2 negatively regulates epidermal growth factor-induced phospholipase C-gamma 1 activity through the direct interaction with tyrosine-phosphorylated phospholipase C-gamma 1Choi, Jang Hyun; Hong, WP; Yun, S, et alARTICLE685 Grb2 negatively regulates epidermal growth factor-induced phospholipase C-gamma 1 activity through the direct interaction with tyrosine-phosphorylated phospholipase C-gamma 1
2005-02Pleckstrin homology domains of phospholipase C-gamma 1 directly interact with beta-tubulin for activation of phospholipase C-gamma 1 and reciprocal modulation of beta-tubulin function in microtubule assemblyChang, JS; Kim, SK; Kwon, TK, et alARTICLE586 Pleckstrin homology domains of phospholipase C-gamma 1 directly interact with beta-tubulin for activation of phospholipase C-gamma 1 and reciprocal modulation of beta-tubulin function in microtubule assembly
2004-08Phospholipase C-gamma 1 is a guanine nucleotide exchange factor for dynamin-1 and enhances dynamin-1-dependent epidermal growth factor receptor endocytosisChoi, Jang Hyun; Park, JB; Bae, SS, et alARTICLE635 Phospholipase C-gamma 1 is a guanine nucleotide exchange factor for dynamin-1 and enhances dynamin-1-dependent epidermal growth factor receptor endocytosis
2004-08Sorting nexin 16 regulates EGF receptor trafficking by phosphatidylinositol-3-phosphate interaction with the Phox domainChoi, Jang Hyun; Hong, WP; Kim, MJ, et alARTICLE643 Sorting nexin 16 regulates EGF receptor trafficking by phosphatidylinositol-3-phosphate interaction with the Phox domain
2003-04Cbl competitively inhibits epidermal growth factor-induced activation of phospholipase C-gamma 1Choi, Jang Hyun; Bae, SS; Park, JB, et alARTICLE538
2002Regulation of phospholipase C-gamma l by protein kinase A-dependent phosphorylationBae, SS; Choi, Jang Hyun; Oh, YS, et alARTICLE675 Regulation of phospholipase C-gamma l by protein kinase A-dependent phosphorylation
2001-02Proteolytic cleavage of epidermal growth factor receptor by caspasesBae, SS; Choi, Jang Hyun; Oh, YS, et alARTICLE515 Proteolytic cleavage of epidermal growth factor receptor by caspases

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