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Choi, Jang Hyun (최장현)

Department
School of Life Sciences(생명과학부)
Research Interests
Diabetes, Metabolic Disorders, PPARg, Gene Regulation, Anti-Diabetic Drug
Lab
Lab of Diabetes and Metabolism (LDM)
Website
http://sites.google.com/site/diabetesandmetabolism/
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2014-11Revisiting PPAR gamma as a target for the treatment of metabolic disordersChoi, Jang Hyun; Park, Jiyoung; Choi, Sun-SilARTICLE901 Revisiting PPAR gamma as a target for the treatment of metabolic disorders
2014-09A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivityChoi, Sun-Sil; Kim, Eun Sun; Koh, Minseob, et alARTICLE805 A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity
2014-07OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ miceYang, Yongryoul; Jang H.J.; Yoon, Sunyoung, et alARTICLE912 OGA heterozygosity suppresses intestinal tumorigenesis in Apc min/+ mice
2014-05Phenotypic screening to identify small-molecule enhancers for glucose uptake: Target identification and rational optimization of their efficacyKoh, Minseob; Park, Jongmin; Koo, Ja Young, et alARTICLE692 Phenotypic screening to identify small-molecule enhancers for glucose uptake: Target identification and rational optimization of their efficacy
2013-04C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle AtrophyKoh, Ara; Lee, Mi Nam; Yang, Yong Ryoul, et alARTICLE809 C1-Ten Is a Protein Tyrosine Phosphatase of Insulin Receptor Substrate 1 (IRS-1), Regulating IRS-1 Stability and Muscle Atrophy
2013-01Phospholipase C-gamma 1 involved in brain disordersJang, Hyun-Jun; Yang, Yong Ryoul; Kim, Jung Kuk, et alARTICLE743 Phospholipase C-gamma 1 involved in brain disorders
2012-11B-cell translocation gene-2 increases hepatic gluconeogenesis via induction of CREBHwang, Seung-Lark; Kwon, Okyun; Lee, Soo Jin, et alARTICLE960 B-cell translocation gene-2 increases hepatic gluconeogenesis via induction of CREB
2012-08Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exerciseMoon, Hyo Youl; Kim, Se Hyun; Yang, Yong Ryoul, et alARTICLE737 Macrophage migration inhibitory factor mediates the antidepressant actions of voluntary exercise
2012-07Beige adipocytes are a distinct type of thermogenic fat cell in mouse and humanWu, Jun; Bostrom, Pontus; Sparks, Lauren M., et alARTICLE886 Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human
2012-06PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-beta 3 (PLC-beta 3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-beta 3 and Somatostatin ReceptorsKim, Jung Kuk; Kwon, Ohman; Kim, Jinho, et alARTICLE849 PDZ Domain-containing 1 (PDZK1) Protein Regulates Phospholipase C-beta 3 (PLC-beta 3)-specific Activation of Somatostatin by Forming a Ternary Complex with PLC-beta 3 and Somatostatin Receptors
2012-06O-GlcNAcase is essential for embryonic development and maintenance of genomic stabilityYang, Yong Ryoul; Song, Minseok; Lee, Ho, et alARTICLE634 O-GlcNAcase is essential for embryonic development and maintenance of genomic stability
2012-02Fibroblast Growth Factor-21 Regulates PPAR gamma Activity and the Antidiabetic Actions of ThiazolidinedionesDutchak, Paul A.; Katafuchi, Takeshi; Bookout, Angie L., et alARTICLE583 Fibroblast Growth Factor-21 Regulates PPAR gamma Activity and the Antidiabetic Actions of Thiazolidinediones
2012-01Diverse cellular and physiological roles of phospholipase C-γ1Yang, Yong Ryoul; Choi, Jang Hyun; Chang, Jong-Soo, et alARTICLE697 Diverse cellular and physiological roles of phospholipase C-γ1
2012-01Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated ReceptorsMalapaka, Raghu R. V.; Khoo, SokKean; Zhang, Jifeng, et alARTICLE577 Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors
2012-01A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesisBostroem, Pontus; Wu, Jun; Jedrychowski, Mark P., et alARTICLE712 A PGC1-alpha-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2011-12N-Acetylfarnesylcysteine Is a Novel Class of Peroxisome Proliferator-activated Receptor gamma Ligand with Partial and Full Agonist Activity in Vitro and in VivoBhalla, Kavita; Hwang, Bor Jang; Choi, Jang Hyun, et alARTICLE577 N-Acetylfarnesylcysteine Is a Novel Class of Peroxisome Proliferator-activated Receptor gamma Ligand with Partial and Full Agonist Activity in Vitro and in Vivo
2011-09Antidiabetic actions of a non-agonist PPAR gamma ligand blocking Cdk5-mediated phosphorylationChoi, Jang Hyun; Banks, Alexander S.; Kamenecka, Theodore M., et alARTICLE584 Antidiabetic actions of a non-agonist PPAR gamma ligand blocking Cdk5-mediated phosphorylation
2011-06Separation of the gluconeogenic and mitochondrial functions of PGC-1 alpha through S6 kinaseLustig, Yaniv; Ruas, Jorge L.; Estall, Jennifer L., et alARTICLE584 Separation of the gluconeogenic and mitochondrial functions of PGC-1 alpha through S6 kinase
2011-02The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1 alpha/ATF6 alpha ComplexWu, Jun; Ruas, Jorge L.; Estall, Jennifer L., et alARTICLE554 The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1 alpha/ATF6 alpha Complex
2010-07Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPAR gamma by Cdk5Choi, Jang Hyun; Banks, Alexander S.; Estall, Jennifer L., et alARTICLE612 Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPAR gamma by Cdk5

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