사진

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Choi, Jang Hyun (최장현)

Department
School of Life Sciences(생명과학부)
Research Interests
Diabetes, Metabolic Disorders, PPARg, Gene Regulation, Anti-Diabetic Drug
Lab
Lab of Diabetes and Metabolism (LDM)
Website
http://sites.google.com/site/diabetesandmetabolism/
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Issue DateTitleAuthor(s)TypeViewAltmetrics
2019-10Phospholipase C-β1 potentiates glucose-stimulated insulin secretionHwang, Hyeon-Jeong; Yang, Yong Ryoul; Kim, Hye Yun, et alARTICLE99 Phospholipase C-β1 potentiates glucose-stimulated insulin secretion
2019-09Rational design and synthesis of reversible covalent PPARγ antagonistic ligands inhibiting Ser273 phosphorylationKim, Hyunsoo; Jo, Ala; Choi, Sun-sil, et alARTICLE140 Rational design and synthesis of reversible covalent PPARγ antagonistic ligands inhibiting Ser273 phosphorylation
2019-03Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppressionHua, Tuyen N.M.; Kim, Min-Kyu; Vo, Vu T.A., et alARTICLE77 Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression
2019-01COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver diseaseLee, Changu; Kim, Min; Lee, Jun Ho, et alARTICLE331 COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease
2019Glucosylceramide synthase regulates adipo-osteogenic differentiation through synergistic activation of PPARγ with GlcCerJang, Hyun-Jun; Lim, Seyoung; Kim, Jung-Min, et alARTICLE50
2018-10The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasomemediated degradation of PPAR gammaLee, Jae Min; Choi, Sun Sil; Lee, Yo Han, et alARTICLE285 The E3 ubiquitin ligase TRIM25 regulates adipocyte differentiation via proteasomemediated degradation of PPAR gamma
2018-09RASAL3 preferentially stimulates GTP hydrolysis of the Rho family small GTPase Rac2Shin, Yoonjae; Kim, Yong Woo; Kim, Hyemin, et alARTICLE236 RASAL3 preferentially stimulates GTP hydrolysis of the Rho family small GTPase Rac2
2018-06Flightless-I Controls Fat Storage in DrosophilaPark, Jung-Eun; Lee, Eun Ji; Kim, Jung Kwan, et alARTICLE295 Flightless-I Controls Fat Storage in Drosophila
2018-05Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channelsHwang, Hyeon-Jeong; Park, Kyoung-Su; Choi, Jang Hyun, et alARTICLE357 Zafirlukast promotes insulin secretion by increasing calcium influx through L-type calcium channels
2018-01Noncanonical agonist PPAR gamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapyKhandekar, Melin J.; Banks, Alexander S.; Laznik-Bogoslavski, Dina, et alARTICLE278 Noncanonical agonist PPAR gamma ligands modulate the response to DNA damage and sensitize cancer cells to cytotoxic chemotherapy
2017-10Forebrain-specific ablation of phospholipase C gamma 1 causes manic-like behaviorYang, YR; Jung, JH; Kim, SJ, et alARTICLE562 Forebrain-specific ablation of phospholipase C gamma 1 causes manic-like behavior
2016-08Mechanistic Elucidation Guided by Covalent Inhibitors for the Development of Anti-diabetic PPARγ LigandsBae, Hwan; Jang, Jun Young; Choi, Sun-Sil, et alARTICLE800 Mechanistic Elucidation Guided by Covalent Inhibitors for the Development of Anti-diabetic PPARγ Ligands
2016-04PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose TissueChoi, Sun-sil; Kim, Eun-Sun; Jung, Ji-Eun, et alARTICLE1037 PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue
2015-12Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivityChoi, Sunsil; Jung, Ji-Eun; Yang, Yong Ryoul, et alARTICLE754 Novel phosphorylation of PPARγ ameliorates obesity-induced adipose tissue inflammation and improves insulin sensitivity
2015-12Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice.Yang, Yong Ryoul; Jang, Hyun-Jun; Choi, Sun-Sil, et alARTICLE671 Obesity resistance and increased energy expenditure by white adipose tissue browning in Oga +/- mice.
2015-05Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signalingYang, Yong Ryoul; Kim, Dae Hyun; Seo, Young-Kyo, et alARTICLE844 Elevated O-GlcNAcylation promotes colonic inflammation and tumorigenesis by modulating NF-κB signaling
2015-03Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRαChoi, Jin Sil; Choi, Sun-Sil; Kim, Eun Sun, et alARTICLE878 Flightless-1, a novel transcriptional modulator of PPARγ through competing with RXRα
2014-11Thrap3 docks on phosphoserine 273 of PPAR gamma and controls diabetic gene programmingChoi, Jang Hyun; Choi, Sun-Sil; Kim, Eun Sun, et alARTICLE710 Thrap3 docks on phosphoserine 273 of PPAR gamma and controls diabetic gene programming
2014-11Revisiting PPAR gamma as a target for the treatment of metabolic disordersChoi, Jang Hyun; Park, Jiyoung; Choi, Sun-SilARTICLE838 Revisiting PPAR gamma as a target for the treatment of metabolic disorders
2014-09A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivityChoi, Sun-Sil; Kim, Eun Sun; Koh, Minseob, et alARTICLE735 A novel non-agonist peroxisome proliferator-activated receptor γ (PPARγ) ligand UHC1 blocks PPARγ phosphorylation by cyclin-dependent kinase 5 (CDK5) and improves insulin sensitivity

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