사진

  • ResearcherID
  • ResearchGate
  • Scopus

Kwon, Hyug Moo (권혁무)

Department
Department of Biological Sciences(생명과학과)
Website
http://ikd.unist.ac.kr/
Lab
Immunometabolism and Cancer Lab. (면역대사와 암 실험실)
Research Keywords
만성염증질환, 뇌질환, 신장질환, 비만, 암, 유전체 불안정성, 대사 증후군, Chronic inflammatory diseases, Brain disorder, Kidney disorder, Obesity, Cancer, TonEBP, Genomic instability, Metabolic syndrome
Research Interests
Emerging data revealed the critical role of the TonEBP (NFAT5), initially identified as a central DNA binding transcription factors, in inflammatory diseases including rheumatoid arthritis, atherosclerosis, and chronic kidney disease. We suggested that TonEBP is a critical factor in diet-induced obesity, cancer, brain disorders and autoimmune disease. Our research group investigates cellular and molecular pathway of TonEBP action in a variety of inflammatory diseases and develops anti-inflammatory agents targeting TonEBP.
This table browses all dspace content
Issue DateTitleAuthor(s)TypeViewAltmetrics
2020-09TonEBP Promotes beta-Cell Survival under ER Stress by Enhancing AutophagyKang, Hyun Je; Yoo, Eun Jin; Lee, Hwan Hee, et alARTICLE21 TonEBP Promotes beta-Cell Survival under ER Stress by Enhancing Autophagy
2020-08Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistanceLee, Jun Ho; Suh, Jae Hee; Kang, Hyun Je, et alARTICLE17 Tonicity-responsive enhancer-binding protein promotes stemness of liver cancer and cisplatin resistance
2020-06TonEBP in dendritic cells mediates pro-inflammatory maturation and Th1/Th17 responsesYe, Byeong Jin; Lee, Hwan Hee; Yoo, Eun Jin, et alARTICLE94 TonEBP in dendritic cells mediates pro-inflammatory maturation and Th1/Th17 responses
2019-10Tonicity-responsive enhancer binding protein (TonEBP) regulates TNF-alpha-induced hypothalamic inflammationKim, Han Rae; Kim, Dong Hee; Kim, Kwang Kon, et alARTICLE167 Tonicity-responsive enhancer binding protein (TonEBP) regulates TNF-alpha-induced hypothalamic inflammation
2019-10Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney InjuryYoo, Eun Jin; Lim, Sun Woo; Kang, Hyun Je, et alARTICLE186 Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury
2019-09TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1Kang, Hyun Je; Park, Hyun; Yoo, Eun Jin, et alARTICLE210 TonEBP Regulates PCNA Polyubiquitination in Response to DNA Damage through Interaction with SHPRH and USP1
2019-08TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beigingLee, Hwan Hee; An, Seung Min; Ye, Byeong Jin, et alARTICLE273 TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beiging
2019-04TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its PromoterYoo, Eun Jin; Lee, Hwan Hee; Ye, Byeong Jin, et alARTICLE170 TonEBP Suppresses the HO-1 Gene by Blocking Recruitment of Nrf2 to Its Promoter
2019-02Tonicity-responsive enhancer-binding protein promotes hepatocellular carcinogenesis, recurrence and metastasisLee, Jun Ho; Suh, Jae Hee; Choi, Soo Youn, et alARTICLE422 Tonicity-responsive enhancer-binding protein promotes hepatocellular carcinogenesis, recurrence and metastasis
2019-01COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver diseaseLee, Changu; Kim, Min; Lee, Jun Ho, et alARTICLE541 COL6A3-derived endotrophin links reciprocal interactions among hepatic cells in the pathology of chronic liver disease
2018-07Transcription Factor NFAT5 Promotes Migration and Invasion of Rheumatoid Synoviocytes via Coagulation Factor III and CCL2Lee, Saseong; Kong, Jin-Sun; You, Sungyong, et alARTICLE267 Transcription Factor NFAT5 Promotes Migration and Invasion of Rheumatoid Synoviocytes via Coagulation Factor III and CCL2
2018-03Optical properties of acute kidney injury measured by quantitative phase imagingBan, Sungbea; Min, Eunjung; Baek, Songyee, et alARTICLE487 Optical properties of acute kidney injury measured by quantitative phase imaging
2018-02Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal InjuryChoi, Soo Youn; Lim, Sun Woo; Salimi, Shabnam, et alARTICLE641 Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal Injury
2017-08TonEBP/NFAT5 haploinsufficiency attenuates hippocampal inflammation in high-fat diet/streptozotocin-induced diabetic miceLee, Jong Youl; Jeong, Eun Ae; Kim, Kyung Eun, et alARTICLE544 TonEBP/NFAT5 haploinsufficiency attenuates hippocampal inflammation in high-fat diet/streptozotocin-induced diabetic mice
2017-05Roles of fluid shear stress and retinoic acid in the differentiation of primary cultured human podocytesYang, Seung Hee; Choi, Jin Woo; Huh, Dongeun, et alARTICLE457 Roles of fluid shear stress and retinoic acid in the differentiation of primary cultured human podocytes
2017-04Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding InhibitorsHan, Eun-Jin; Kim, Hyun Young; Lee, Naeun, et alARTICLE691 Suppression of NFAT5-mediated Inflammation and Chronic Arthritis by Novel κB-binding Inhibitors
2017-03Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritisChoi, Susanna; You, Sungyong; Kim, Donghyun, et alARTICLE556 Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis
2016-06Inflammatory signals induce the expression of tonicity-responsive enhancer binding protein (TonEBP) in microgliaJeong, Ga Ram; Im, Sun-Kyoung; Bae, Yun-Hee, et alARTICLE820 Inflammatory signals induce the expression of tonicity-responsive enhancer binding protein (TonEBP) in microglia
2016-05TonEBP suppresses IL-10-mediated immunomodulationChoi, Soo Youn; Lee, Hwan Hee; Lee, Jun Ho, et alARTICLE771 TonEBP suppresses IL-10-mediated immunomodulation
2016-04PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose TissueChoi, Sun-sil; Kim, Eun-Sun; Jung, Ji-Eun, et alARTICLE1257 PPAR gamma Antagonist Gleevec Improves Insulin Sensitivity and Promotes the Browning of White Adipose Tissue

MENU