Kang, Sebyung (강세병)

Department

Department of Biological Sciences(생명과학과)

Website

https://sites.google.com/site/proteinnanobio

Lab

Protein Nanobio Lab. (단백질 나노바이오 연구실)

Research Keywords

바이오 센서, 바이오 이미징, 나노바이오기술, 단백질 공학, 단백질 나노입자, 세포질내 단백질 전달, Nanobiotechnology, Protein Engineering, Protein Nanoparticle-based Drug Delivery, Biosensors, Bioimaging

Research Interests

Our researches focus on utilizing protein based nanobio-templates for  biomedical and biomaterial applications. To achieve these goals, we are using various types of nanobio-templates, such as viral capsids, small protein cages, and functional proteins, and biophysical and biochemical methods to elucidate their functions.
1. Protein Cage EngineeringProtein cage architecture has three modifiable surfaces; exterior, interior and subunit-subunit interfaces. These surfaces can be modified both genetically and chemically on demand. We can engineer these three surfaces for the purposes listed below by design.
 2. Targeted Delivery of Therapeutic or Diagnostic ReagentsNanobio-templates can be utilized as multivalent and targeted delivery vehicles through genetic and chemical modifications. Well defined 3-D structure and multiple addressible sites are beneficial for multi-functional nanoplatforms.
3. Protein engineering: Biosensings & Imaging Binding specificity and high affinity to any given target molecule are essential features for in vitro and/or in vivo diagnostics and for many other biotechnological and biomedical applications. Protein engineering allows constructing multifunctional biosensing & imaging components.