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dc.citation.endPage 7256 -
dc.citation.number 13 -
dc.citation.startPage 7248 -
dc.citation.title JOURNAL OF VIROLOGY -
dc.citation.volume 78 -
dc.contributor.author Lim, Chunghun -
dc.contributor.author Choi, Changtaek -
dc.contributor.author Choe, Joonho -
dc.date.accessioned 2023-12-22T10:45:27Z -
dc.date.available 2023-12-22T10:45:27Z -
dc.date.created 2015-01-05 -
dc.date.issued 2004-07 -
dc.description.abstract Latency-associated nuclear antigen 1 (LANA1) of Kaposi's sarcoma-associated herpesvirus (KSHV) is implicated in the persistence of the viral genome during latent infection. It has been suggested that LANA1 tethers the viral genome to the host chromosome and also participates actively in DNA replication from the terminal repeat of KSHV. Here we show by mutational analysis that the mitotic chromosome-binding activity of LANA1 is tightly coupled to its replication activity. Thus, KSHV appears to have evolved a unique tactic for its stable maintenance. -
dc.identifier.bibliographicCitation JOURNAL OF VIROLOGY, v.78, no.13, pp.7248 - 7256 -
dc.identifier.doi 10.1128/JVI.78.13.7248-7356.2004 -
dc.identifier.issn 0022-538X -
dc.identifier.scopusid 2-s2.0-2942635073 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/9819 -
dc.identifier.url http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=2942635073 -
dc.identifier.wosid 000222153800056 -
dc.language 영어 -
dc.publisher AMER SOC MICROBIOLOGY -
dc.title Mitotic chromosome-binding activity of latency-associated nuclear antigen 1 is required for DNA replication from terminal repeat sequence
of Kaposi's sarcoma-associated herpesvirus
-
dc.type Article -
dc.description.journalRegisteredClass scopus -

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