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DC Field | Value | Language |
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dc.citation.endPage | 1638 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1632 | - |
dc.citation.title | ADVANCED FUNCTIONAL MATERIALS | - |
dc.citation.volume | 22 | - |
dc.contributor.author | Lee, Jiseok | - |
dc.contributor.author | Seo, Sungbaek | - |
dc.contributor.author | Kim, Jinsang | - |
dc.date.accessioned | 2023-12-22T05:12:27Z | - |
dc.date.available | 2023-12-22T05:12:27Z | - |
dc.date.created | 2014-12-23 | - |
dc.date.issued | 2012-04 | - |
dc.description.abstract | Rationally designed polydiacetylene (PDA) molecules have been developed for rapid, selective, sensitive, and convenient colorimetric detection of organophosphate (OP) nerve agents, a mass destruction weapon. Oxime (OX) functionality was incorporated into diacetylene molecules to utilize its strong affinity toward organophosphates. The diacetylene molecules having an OX functional group (OX-PDA) were self-assembled to form PDA liposomes in an aqueous solution. Upon exposure to organophosphate nerve agent simulants, OX at the OX-PDA liposome surface interacts with nerve agent simulants, which results in intraliposomal repulsive stress due to steric repulsion between OP-occupied OX units at the liposome surface as well as interliposomal aggregation induced by increased hydrophobicity of the liposome surface via OP-OX complex formation. The resulting intra- and interliposomal stress causes disturbance of the conjugated backbone of OX-PDA, producing color change as a label-free and sensitive sensory signal. The effects of molecular structure on selectivity and sensitivity of OX-PDA liposome solution, OX-PDA liposome-embedded agarose gels, and OX-PDA liposome-coated cellulose acetate membranes were systematically investigated. The optimized OX-PDA liposome in the solid state showed selective and rapid optical transition upon exposure down to 160 ppb of diisopropylfluorophosphate (DFP), a nerve agent simulant. The results provide an insightful molecular design principle of PDA-based colorimetric sensor and suggest portable sensory patches for rapid, selective, sensitive, and convenient colorimetric detection of organophosphate nerve agents. | - |
dc.identifier.bibliographicCitation | ADVANCED FUNCTIONAL MATERIALS, v.22, no.8, pp.1632 - 1638 | - |
dc.identifier.doi | 10.1002/adfm.201102486 | - |
dc.identifier.issn | 1616-301X | - |
dc.identifier.scopusid | 2-s2.0-84859837762 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/9595 | - |
dc.identifier.wosid | 000302794400009 | - |
dc.language | 영어 | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Colorimetric Detection of Warfare Gases by Polydiacetylenes Toward Equipment-Free Detection | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | polydiacetylene | - |
dc.subject.keywordAuthor | liposomes | - |
dc.subject.keywordAuthor | self-assembly | - |
dc.subject.keywordAuthor | oxime | - |
dc.subject.keywordAuthor | nerve agents | - |
dc.subject.keywordPlus | SUPRAMOLECULES | - |
dc.subject.keywordPlus | FLUORESCENT | - |
dc.subject.keywordPlus | CRYSTALS | - |
dc.subject.keywordPlus | SENSORS | - |
dc.subject.keywordPlus | AGENTS | - |
dc.subject.keywordPlus | FILMS | - |
dc.subject.keywordPlus | REVERSIBILITY | - |
dc.subject.keywordPlus | MECHANISM | - |
dc.subject.keywordPlus | SURFACES | - |
dc.subject.keywordPlus | CHROMISM | - |
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