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Lee, Jiseok
Synthesis of Polymeric Optical Nano/Micro-architectures lab
Research Interests
  • Optofluidic photolithography
  • Nanoparticle Synthesis
  • Conjugated polymer design and Synthesis
  • Flow lithography
  • 3d printing

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Polydiacetylene Liposome Microarray Toward Influenza A Virus Detection: Effect of Target Size on Turn-On Signaling

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dc.contributor.author Seo, Sungbaek ko
dc.contributor.author Lee, Jiseok ko
dc.contributor.author Choi, Eun-Jin ko
dc.contributor.author Kim, Eun-Ju ko
dc.contributor.author Song, Jae-Young ko
dc.contributor.author Kim, Jinsang ko
dc.date.available 2014-12-24T00:16:55Z -
dc.date.created 2014-12-23 ko
dc.date.issued 2013-05 -
dc.identifier.citation MACROMOLECULAR RAPID COMMUNICATIONS, v.34, no.9, pp.743 - 748 ko
dc.identifier.issn 1022-1336 ko
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/9587 -
dc.description.abstract Target size effect on the sensory signaling intensity of polydiacetylene (PDA) liposome microarrays was systematically investigated. Influenza A virus M1 peptide and M1 antibody were selected as a probetarget pair. While red fluorescence from the PDA liposome microarrays was observed when the larger M1 antibody was used as a target, when the same M1 antibody was used as a probe to detect the smaller M1 peptide sensory signal did not appear. The results reveal that the intensity of the PDA sensory signal is mainly related to the steric repulsion between probetarget complexes not the strength of the probetarget binding force. Based on this finding, we devised a PDA sensory system that directly detects influenza A whole virus as a larger target, and confirmed the target size effect on the signaling efficiency of PDA. ko
dc.description.statementofresponsibility close -
dc.language ENG ko
dc.publisher WILEY-V C H VERLAG GMBH ko
dc.subject conjugated polymers ko
dc.subject influenza A virus ko
dc.subject liposome microarray ko
dc.subject sensors ko
dc.subject target size ko
dc.title Polydiacetylene Liposome Microarray Toward Influenza A Virus Detection: Effect of Target Size on Turn-On Signaling ko
dc.type ARTICLE ko
dc.identifier.scopusid 2-s2.0-84877262313 ko
dc.identifier.wosid 000318354500007 ko
dc.type.rims ART ko
dc.description.wostc 7 *
dc.date.tcdate 2015-05-06 *
dc.identifier.doi 10.1002/marc.201200819 ko
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