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Park, Jiyoung
Molecular Metabolism Laboratory (MML)
Research Interests
  • Obesity, diabetes, adipose tissue, cancer, cancer-associated adipocyte, dermal adipocyte, metabolic memory


Hyperglycemia as a risk factor for cancer progression

DC Field Value Language Ryu, Tae Young ko Park, Jiyoung ko Scherer, Philipp E. ko 2014-11-26T00:09:56Z - 2014-11-25 ko 2014-10 ko
dc.identifier.citation DIABETES AND METABOLISM JOURNAL, v.38, no.5, pp.330 - 336 ko
dc.identifier.issn 2233-6079 ko
dc.identifier.uri -
dc.description.abstract As the prevalence of diabetes mellitus is substantially increasing worldwide, associated diseases such as renal failure, cardiovascular diseases, fatty liver, and cancers have also increased. A number of cancers such as pancreatic, liver, breast, and female reproductive cancers have shown an increased prevalence and a higher mortality rate in diabetic patients compared to healthy subjects. Thus, this suggests an association between diabetes, especially type 2 diabetes and cancer incidence and progression. Recent studies have suggested that hyperinsulinemia, chronic inflammation and hyperglycemia, all frequently seen in diabetics, may lead to increased tumor growth; the underlying molecular mechanisms of this association are not fully understood. In particular, chronic hyperglycemic episodes could serve as a direct or indirect mediator of the increase in tumor cell growth. Here, we will discuss our current understanding how hyperglycemia and cancer risk may be linked, and what the implications are for the treatment of diabetic cancer patients. ko
dc.description.statementofresponsibility open -
dc.language 영어 ko
dc.publisher 대한당뇨병학회 ko
dc.title Hyperglycemia as a risk factor for cancer progression ko
dc.type ARTICLE ko
dc.identifier.scopusid 2-s2.0-84908891835 ko
dc.type.rims ART ko
dc.description.scopustc 0 * 2014-11-25 *
dc.identifier.doi 10.4093/dmj.2014.38.5.330 ko
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