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Rhee, Hyun-Woo
Biomimetic Chemistry Lab
Research Interests
  • Site-Specific Protein Labeling in Living Cells
  • Artificial Cofactors for Biomimetic Catalyst
  • Spatiotemporal Proteome mapping of living cells

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Activity-based fluorescent probes for monitoring sulfatase activity

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Title
Activity-based fluorescent probes for monitoring sulfatase activity
Author
Park, Hyun-JooRhee, Hyun-WooHong, Jong-In
Keywords
Activity-based probe; Fluorescence; Sulfatase
Issue Date
2012-08
Publisher
PERGAMON-ELSEVIER SCIENCE LTD
Citation
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.22, no.15, pp.4939 - 4941
Abstract
A small-molecule probe for sulfatase is developed that shows a significant change in fluorescence upon reaction with sulfatase in an activity-based manner. As this probe is free from interference from background fluorescence caused by an unreacted probe, it could be a simple and efficient tool for the study of sulfatase activity.
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DOI
10.1016/j.bmcl.2012.06.045
ISSN
0960-894X
Appears in Collections:
PHY_Journal Papers
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