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- Rhee, Hyun-Woo
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Activity-based fluorescent probes for monitoring sulfatase activity
- Author(s)
- Park, Hyun-Joo, Rhee, Hyun-Woo, Hong, Jong-In
- Issued Date
- 2012-08
- Citation
- BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.22, no.15, pp.4939 - 4941
- Abstract
- A small-molecule probe for sulfatase is developed that shows a significant change in fluorescence upon reaction with sulfatase in an activity-based manner. As this probe is free from interference from background fluorescence caused by an unreacted probe, it could be a simple and efficient tool for the study of sulfatase activity.
- Publisher
- PERGAMON-ELSEVIER SCIENCE LTD
- ISSN
- 0960-894X
- Keyword (Author)
- Activity-based probe, Fluorescence, Sulfatase
- Keyword
- BREAST-CANCER, STEROID SULFATASE, RECOGNITION, INHIBITION, MECHANISM, TOOLS
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