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| DC Field | Value | Language |
|---|---|---|
| dc.citation.number | 6706 | - |
| dc.citation.startPage | eadj1182 | - |
| dc.citation.title | SCIENCE | - |
| dc.citation.volume | 385 | - |
| dc.contributor.author | Verma, Anurag | - |
| dc.contributor.author | Huffman, Jennifer E. | - |
| dc.contributor.author | Rodriguez, Alex | - |
| dc.contributor.author | Conery, Mitchell | - |
| dc.contributor.author | Liu, Molei | - |
| dc.contributor.author | Ho, Yuk-Lam | - |
| dc.contributor.author | Kim, Youngdae | - |
| dc.contributor.author | Heise, David A. | - |
| dc.contributor.author | Guare, Lindsay | - |
| dc.contributor.author | Panickan, Vidul Ayakulangara | - |
| dc.contributor.author | Garcon, Helene | - |
| dc.contributor.author | Linares, Franciel | - |
| dc.contributor.author | Costa, Lauren | - |
| dc.contributor.author | Goethert, Ian | - |
| dc.contributor.author | Tipton, Ryan | - |
| dc.contributor.author | Honerlaw, Jacqueline | - |
| dc.contributor.author | Davies, Laura | - |
| dc.contributor.author | Whitbourne, Stacey | - |
| dc.contributor.author | Cohen, Jeremy | - |
| dc.contributor.author | Posner, Daniel C. | - |
| dc.contributor.author | Sangar, Rahul | - |
| dc.contributor.author | Murray, Michael | - |
| dc.contributor.author | Wang, Xuan | - |
| dc.contributor.author | Dochtermann, Daniel R. | - |
| dc.contributor.author | Devineni, Poornima | - |
| dc.contributor.author | Shi, Yunling | - |
| dc.contributor.author | Nandi, Tarak Nath | - |
| dc.contributor.author | Assimes, Themistocles L. | - |
| dc.contributor.author | Brunette, Charles A. | - |
| dc.contributor.author | Carroll, Robert J. | - |
| dc.contributor.author | Clifford, Royce | - |
| dc.contributor.author | Duvall, Scott | - |
| dc.contributor.author | Gelernter, Joel | - |
| dc.contributor.author | Hung, Adriana | - |
| dc.contributor.author | Iyengar, Sudha K. | - |
| dc.contributor.author | Joseph, Jacob | - |
| dc.contributor.author | Kember, Rachel | - |
| dc.contributor.author | Kranzler, Henry | - |
| dc.contributor.author | Kripke, Colleen M. | - |
| dc.contributor.author | Levey, Daniel | - |
| dc.contributor.author | Luoh, Shiuh-Wen | - |
| dc.contributor.author | Merritt, Victoria C. | - |
| dc.contributor.author | Overstreet, Cassie | - |
| dc.contributor.author | Deak, Joseph D. | - |
| dc.contributor.author | Grant, Struan F A | - |
| dc.contributor.author | Polimanti, Renato | - |
| dc.contributor.author | Roussos, Panos | - |
| dc.contributor.author | Shakt, Gabrielle | - |
| dc.contributor.author | Sun, Yan V. | - |
| dc.contributor.author | Tsao, Noah | - |
| dc.contributor.author | Venkatesh, Sanan | - |
| dc.contributor.author | Voloudakis, Georgios | - |
| dc.contributor.author | Justice, Amy | - |
| dc.contributor.author | Begoli, Edmon | - |
| dc.contributor.author | Ramoni, Rachel | - |
| dc.contributor.author | Tourassi, Georgia | - |
| dc.contributor.author | Pyarajan, Saiju | - |
| dc.contributor.author | Tsao, Philip | - |
| dc.contributor.author | O'Donnell, Christopher J. | - |
| dc.contributor.author | Muralidhar, Sumitra | - |
| dc.contributor.author | Moser, Jennifer | - |
| dc.contributor.author | Casas, Juan P. | - |
| dc.contributor.author | Bick, Alexander G. | - |
| dc.contributor.author | Zhou, Wei | - |
| dc.contributor.author | Cai, Tianxi | - |
| dc.contributor.author | Voight, Benjamin F. | - |
| dc.contributor.author | Cho, Kelly | - |
| dc.contributor.author | Gaziano, J Michael | - |
| dc.contributor.author | Madduri, Ravi K. | - |
| dc.contributor.author | Damrauer, Scott | - |
| dc.contributor.author | Liao, Katherine P. | - |
| dc.date.accessioned | 2024-08-09T13:35:06Z | - |
| dc.date.available | 2024-08-09T13:35:06Z | - |
| dc.date.created | 2024-08-09 | - |
| dc.date.issued | 2024-07 | - |
| dc.description.abstract | One of the justifiable criticisms of human genetic studies is the underrepresentation of participants from diverse populations. Lack of inclusion must be addressed at-scale to identify causal disease factors and understand the genetic causes of health disparities. We present genome-wide associations for 2068 traits from 635,969 participants in the Department of Veterans Affairs Million Veteran Program, a longitudinal study of diverse United States Veterans. Systematic analysis revealed 13,672 genomic risk loci; 1608 were only significant after including non-European populations. Fine-mapping identified causal variants at 6318 signals across 613 traits. One-third (n = 2069) were identified in participants from non-European populations. This reveals a broadly similar genetic architecture across populations, highlights genetic insights gained from underrepresented groups, and presents an extensive atlas of genetic associations. | - |
| dc.identifier.bibliographicCitation | SCIENCE, v.385, no.6706, pp.eadj1182 | - |
| dc.identifier.doi | 10.1126/science.adj1182 | - |
| dc.identifier.issn | 0036-8075 | - |
| dc.identifier.scopusid | 2-s2.0-85199126998 | - |
| dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/83431 | - |
| dc.language | 영어 | - |
| dc.publisher | AMER ASSOC ADVANCEMENT SCIENCE | - |
| dc.title | Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program | - |
| dc.type | Article | - |
| dc.description.isOpenAccess | FALSE | - |
| dc.type.docType | Article | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
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