Optical mobility of blood cells for label-free cell separation applications

Abstract

This paper describes the optical mobilities of blood cell components. Blood cells are heterogeneous, and their optical behaviors depend on size, morphology, and other optical properties. In a step toward the label-free separation of blood cells, the optical mobility resulting from the optical scattering and cell properties was derived and evaluated for each cell component. The optical mobilities of red blood cells, lymphocytes, granulocytes, and monocytes were measured under various flow conditions of a cross-type optical particle separator. (C) 2013 AIP Publishing LLC