Full metadata record
DC Field | Value | Language |
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dc.citation.number | 1 | - |
dc.citation.startPage | 386 | - |
dc.citation.title | NANOSCALE RESEARCH LETTERS | - |
dc.citation.volume | 7 | - |
dc.contributor.author | Li, Lei | - |
dc.contributor.author | Zhao, Jin-Feng | - |
dc.contributor.author | Won, Nayoun | - |
dc.contributor.author | Jin, Ho | - |
dc.contributor.author | Kim, Sungjee | - |
dc.contributor.author | Chen, Ji-Yao | - |
dc.date.accessioned | 2024-03-11T18:05:11Z | - |
dc.date.available | 2024-03-11T18:05:11Z | - |
dc.date.created | 2024-03-11 | - |
dc.date.issued | 2012-12 | - |
dc.description.abstract | Sulfonated aluminum phthalocyanines (AlPcSs), commonly used photosensitizers for photodynamic therapy of cancers (PDT), were conjugated with amine-dihydrolipoic acid-coated quantum dots (QDs) by electrostatic binding, achieving 70 AlPcSs per QD. The AlPcS-QD conjugates can utilize the intense light absorptions of conjugated QDs to indirectly excite AlPcSs producing singlet oxygen via fluorescence resonance energy transfer (FRET), demonstrating a new excitation model for PDT. The AlPcS-QD conjugates easily penetrated into human nasopharyngeal carcinoma cells and carried out the FRET in cells, with efficiency around 80%. Under the irradiation of a 532-nm laser, which is at the absorption region of QDs but not fit for the absorption of AlPcSs, the cellular AlPcS-QD conjugates can destroy most cancer cells via FRET-mediated PDT, showing the potential of this new strategy for PDT. | - |
dc.identifier.bibliographicCitation | NANOSCALE RESEARCH LETTERS, v.7, no.1, pp.386 | - |
dc.identifier.doi | 10.1186/1556-276X-7-386 | - |
dc.identifier.issn | 1931-7573 | - |
dc.identifier.scopusid | 2-s2.0-84866106511 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/81559 | - |
dc.identifier.wosid | 000319010500001 | - |
dc.language | 영어 | - |
dc.publisher | SPRINGER | - |
dc.title | Quantum dot-aluminum phthalocyanine conjugates perform photodynamic reactions to kill cancer cells via fluorescence resonance energy transfer | - |
dc.type | Article | - |
dc.description.isOpenAccess | TRUE | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics; Materials Science; Physics | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | Quantum dot | - |
dc.subject.keywordAuthor | Aluminum phthalocyanine | - |
dc.subject.keywordAuthor | Fluorescence resonance energy transfer | - |
dc.subject.keywordAuthor | Photodynamic therapy of cancers | - |
dc.subject.keywordPlus | SINGLET OXYGEN | - |
dc.subject.keywordPlus | FRET MICROSCOPY | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | GENERATION | - |
dc.subject.keywordPlus | ANION | - |
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