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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 2541 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 2535 | - |
dc.citation.title | BIOMATERIALS | - |
dc.citation.volume | 31 | - |
dc.contributor.author | Ku, Sook Hee | - |
dc.contributor.author | Ryu, Jungki | - |
dc.contributor.author | Hong, Seon Ki | - |
dc.contributor.author | Lee, Haeshin | - |
dc.contributor.author | Park, Chan Beum | - |
dc.date.accessioned | 2023-12-22T07:12:07Z | - |
dc.date.available | 2023-12-22T07:12:07Z | - |
dc.date.created | 2014-10-06 | - |
dc.date.issued | 2010-03 | - |
dc.description.abstract | We present a versatile route for promoting cell adhesion and viability on various non-wetting surfaces, inspired by mussel adhesion mechanism. The oxidative polymerization of dopamine, a small designer molecule of the DOPA-K motif found in mussels, results in the formation of a poly(dopamine) ad-layer on any material surface. We found that the poly(dopamine) coating can promote cell adhesion on any type of material surfaces including the well-known anti-adhesive substrate, poly(tetrafluoroethylene). According to our results, mammalian cells well adhered and underwent general cell adhesion processes (i.e., attachment to substrate, spreading, and cytoskeleton development) on poly(dopamine)-modified surfaces, while they barely adhered and spread on unmodified non-wetting surfaces. The mussel-inspired surface functionalization strategy is extremely useful because it does not require the time-consuming synthesis of complex linkers and the process is solvent-free and non-toxic. Therefore, it can be a powerful route for converting a variety of bioinert substrates into bioactive ones. | - |
dc.identifier.bibliographicCitation | BIOMATERIALS, v.31, no.9, pp.2535 - 2541 | - |
dc.identifier.doi | 10.1016/j.biomaterials.2009.12.020 | - |
dc.identifier.issn | 0142-9612 | - |
dc.identifier.scopusid | 2-s2.0-74449090189 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/6912 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=74449090189 | - |
dc.identifier.wosid | 000275348800010 | - |
dc.language | 영어 | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.title | General functionalization route for cell adhesion on non-wetting surfaces | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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