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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 8853 | - |
dc.citation.number | 40 | - |
dc.citation.startPage | 8848 | - |
dc.citation.title | JOURNAL OF MATERIALS CHEMISTRY | - |
dc.citation.volume | 20 | - |
dc.contributor.author | Lee, Minah | - |
dc.contributor.author | Ku, Sook Hee | - |
dc.contributor.author | Ryu, Jungki | - |
dc.contributor.author | Park, Chan Beum | - |
dc.date.accessioned | 2023-12-22T07:36:33Z | - |
dc.date.available | 2023-12-22T07:36:33Z | - |
dc.date.created | 2014-10-06 | - |
dc.date.issued | 2010 | - |
dc.description.abstract | Hydroxyapatite (HAp)/carbon nanotubes (CNTs) hybrid composite materials are successfully synthesized via a biomineralization process that employs poly(dopamine) (PDA), a synthetic mimic of mussel adhesive proteins. Creating bio-inorganic composites for regenerative medicine requires appropriate fillers to enhance their mechanical robustness; for example, natural bones are composed mainly of HAp supported by collagen fibers. In this regard, many efforts have been made to harness HAp as a bone substitute through its integration with reinforcing fibrous materials such as CNTs. We found that the formation of a PDA ad-layer on the surface of CNTs changed the hydrophobic CNTs to become bioactive. This enabled efficient interaction between the CNTs and mineral ions (e.g., Ca2+), which facilitated the mineralization of HAp. CNTs functionalized with PDA (CNT-PDA) highly accelerated the formation of HAp when incubated in a simulated body fluid and exhibited a minimal cytotoxic effect on bone osteoblast cells compared to pristine or carboxylated CNTs. Our results show the potential of CNT-PDA as a scaffold material for bone tissue regeneration and implantation. | - |
dc.identifier.bibliographicCitation | JOURNAL OF MATERIALS CHEMISTRY, v.20, no.40, pp.8848 - 8853 | - |
dc.identifier.doi | 10.1039/c0jm01339k | - |
dc.identifier.issn | 0959-9428 | - |
dc.identifier.scopusid | 2-s2.0-77957769711 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/6895 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77957769711 | - |
dc.identifier.wosid | 000282518200011 | - |
dc.language | 영어 | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Mussel-inspired functionalization of carbon nanotubes for hydroxyapatite mineralization | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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