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Ryu, Jungki
Bioinspired Functional Materials Lab.
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dc.citation.endPage 7206 -
dc.citation.number 16 -
dc.citation.startPage 7201 -
dc.citation.title SOFT MATTER -
dc.citation.volume 7 -
dc.contributor.author Ryu, Jungki -
dc.contributor.author Ku, Sook Hee -
dc.contributor.author Lee, Minah -
dc.contributor.author Park, Chan Beum -
dc.date.accessioned 2023-12-22T06:38:04Z -
dc.date.available 2023-12-22T06:38:04Z -
dc.date.created 2014-10-06 -
dc.date.issued 2011 -
dc.description.abstract Inspired by nature's strategy for creating organic/inorganic hybrid composite materials, we developed a simple but powerful method to synthesize bone-like peptide/hydroxyapatite nanocomposites using a mussel-mimetic adhesive, polydopamine. We found that polydopamine was uniformly coated in a graphite-like layered structure on the surface of self-assembled diphenylalanine (Phe-Phe, FF) nanowires and enabled the epitaxial growth of c-axis-oriented hydroxyapatite nanocrystals along the nanowires, which is similar to mineralized collagen nanofibers of natural bone. The mineralized peptide nanowires were further organized in relation to each other and then readily hybridized with osteoblastic cells, resulting in the formation of multi-level hierarchical structures. They were found to be nontoxic and enabled efficient adhesion and proliferation of osteoblastic cells by guiding filopoidal extension. -
dc.identifier.bibliographicCitation SOFT MATTER, v.7, no.16, pp.7201 - 7206 -
dc.identifier.doi 10.1039/c1sm05307h -
dc.identifier.issn 1744-683X -
dc.identifier.scopusid 2-s2.0-79961152803 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/6893 -
dc.identifier.url http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79961152803 -
dc.identifier.wosid 000293412900011 -
dc.language 영어 -
dc.publisher ROYAL SOC CHEMISTRY -
dc.title Bone-like peptide/hydroxyapatite nanocomposites assembled with multi-level hierarchical structures -
dc.type Article -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -

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