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- Cho, Yoon-Kyoung
- FRUITS Lab.
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| DC Field | Value | Language |
|---|---|---|
| dc.citation.endPage | 7734 | - |
| dc.citation.number | 25 | - |
| dc.citation.startPage | 7732 | - |
| dc.citation.title | LANGMUIR | - |
| dc.citation.volume | 17 | - |
| dc.contributor.author | Cho, Yoon-Kyoung | - |
| dc.contributor.author | Kim, S | - |
| dc.contributor.author | Lim, G | - |
| dc.contributor.author | Granick, Steve | - |
| dc.date.accessioned | 2023-12-22T11:41:11Z | - |
| dc.date.available | 2023-12-22T11:41:11Z | - |
| dc.date.created | 2014-09-05 | - |
| dc.date.issued | 2001-12 | - |
| dc.description.abstract | We report the first use of a surface forces apparatus to study the hybridization of DNA. We study the regime of very high ionic strength (≈1 M) at which commercial DNA chip operations are performed. Using a thiol end-attached single-stranded oligonucleotide, we find that exposure to the complementary strand resulted in larger thickness. In addition, the resistance to small-amplitude shear deformations when opposed to a nonadsorbing surface (mica) increased significantly after hybridization. The thickness at onset of significant shear resistance was, for single-stranded DNA, considerably less than that of hybridized DNA. This could provide a new method to detect DNA hybridization efficiency. | - |
| dc.identifier.bibliographicCitation | LANGMUIR, v.17, no.25, pp.7732 - 7734 | - |
| dc.identifier.doi | 10.1021/la0113769 | - |
| dc.identifier.issn | 0743-7463 | - |
| dc.identifier.scopusid | 2-s2.0-0035846799 | - |
| dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/5914 | - |
| dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0035846799 | - |
| dc.identifier.wosid | 000172590800006 | - |
| dc.language | 영어 | - |
| dc.publisher | AMER CHEMICAL SOC | - |
| dc.title | A surface forces study of DNA hybridization | - |
| dc.type | Article | - |
| dc.description.isOpenAccess | FALSE | - |
| dc.description.journalRegisteredClass | scopus | - |
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