There are no files associated with this item.
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 11 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.title | Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems | - |
dc.citation.volume | 222 | - |
dc.contributor.author | Zhao, Y. | - |
dc.contributor.author | Inayat, S. | - |
dc.contributor.author | Dikin, D.A. | - |
dc.contributor.author | Singer, J.H. | - |
dc.contributor.author | Ruoff, R.S. | - |
dc.contributor.author | Troy, J.B. | - |
dc.date.accessioned | 2023-12-22T09:06:34Z | - |
dc.date.available | 2023-12-22T09:06:34Z | - |
dc.date.created | 2021-10-20 | - |
dc.date.issued | 2008 | - |
dc.description.abstract | The patch clamp technique permits high-resolution recording of the ionic currents flowing through a cell's plasma membrane. In different configurations, this technique has allowed experimenters to record and manipulate the currents that flow either through single ion channels or those that flow across the whole plasma membrane. Unfortunately, the conventional patch clamp method is laborious, requiring the careful fabrication of electrodes, skillful manipulation of the patch pipette towards a cell, and the clever design of electronics and apparatus to allow low-noise recordings. Advances in microfabrication offer promising technologies for high-throughput patch clamp recordings, particularly suitable for drug screening. This paper provides a review of the advances that have been made in the patch clamp technique over the years and considers where application of nanotechnology might provide significant contributions in the future. | - |
dc.identifier.bibliographicCitation | Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems, v.222, no.1, pp.1 - 11 | - |
dc.identifier.doi | 10.1243/17403499JNN149 | - |
dc.identifier.issn | 1740-3499 | - |
dc.identifier.scopusid | 2-s2.0-77956207808 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/54406 | - |
dc.identifier.url | https://journals.sagepub.com/doi/10.1243/17403499JNN149 | - |
dc.language | 영어 | - |
dc.publisher | SAGE | - |
dc.title | Patch clamp technique: Review of the current state of the art and potential contributions from nanoengineering | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.type.docType | Review | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | Automation | - |
dc.subject.keywordAuthor | Electrophysiology | - |
dc.subject.keywordAuthor | Microfabrication | - |
dc.subject.keywordAuthor | Nanoactuation | - |
dc.subject.keywordAuthor | Patch clamp technique | - |
dc.subject.keywordPlus | Clever designs | - |
dc.subject.keywordPlus | Drug screening | - |
dc.subject.keywordPlus | High resolution | - |
dc.subject.keywordPlus | High-throughput | - |
dc.subject.keywordPlus | Ionic current | - |
dc.subject.keywordPlus | Low noise | - |
dc.subject.keywordPlus | Nano-engineering | - |
dc.subject.keywordPlus | Nanoactuation | - |
dc.subject.keywordPlus | Patch clamp method | - |
dc.subject.keywordPlus | Patch clamp recording | - |
dc.subject.keywordPlus | Patch clamp technique | - |
dc.subject.keywordPlus | Patch pipette | - |
dc.subject.keywordPlus | Plasma membranes | - |
dc.subject.keywordPlus | Single-ion channels | - |
dc.subject.keywordPlus | State of the art | - |
dc.subject.keywordPlus | Cell membranes | - |
dc.subject.keywordPlus | Electrophysiology | - |
dc.subject.keywordPlus | Microanalysis | - |
dc.subject.keywordPlus | Micromachining | - |
dc.subject.keywordPlus | Neurology | - |
dc.subject.keywordPlus | Microfabrication | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Tel : 052-217-1404 / Email : scholarworks@unist.ac.kr
Copyright (c) 2023 by UNIST LIBRARY. All rights reserved.
ScholarWorks@UNIST was established as an OAK Project for the National Library of Korea.