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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 5789 | - |
dc.citation.number | 37 | - |
dc.citation.startPage | 5781 | - |
dc.citation.title | ADVANCED FUNCTIONAL MATERIALS | - |
dc.citation.volume | 24 | - |
dc.contributor.author | Choi, Yuri | - |
dc.contributor.author | Kim, Seongchan | - |
dc.contributor.author | Choi, Myung-Ho | - |
dc.contributor.author | Ryoo, Soo-Ryoon | - |
dc.contributor.author | Park, Jongnam | - |
dc.contributor.author | Min, Dal-Hee | - |
dc.contributor.author | Kim, Byeong-Su | - |
dc.date.accessioned | 2023-12-22T02:10:35Z | - |
dc.date.available | 2023-12-22T02:10:35Z | - |
dc.date.created | 2014-08-11 | - |
dc.date.issued | 2014-10 | - |
dc.description.abstract | Photosensitizers (PSs) are light-sensitive molecules that are highly hydrophobic, which poses a challenge to their use for targeted photodynamic therapy. Hence, considerable efforts have been made to develop carriers for the delivery of PSs. Herein, a novel design is described of highly biocompatible, fluorescent, folic acid (FA)-functionalized carbon nanodots (CDs) as carriers for the PS zinc phthalocyanine (ZnPc) to achieve simultaneous biological imaging and targeted photodynamic therapy. FA is modified on PEG--passivated CDs (CD-PEG) for targeted delivery to FA-positive cancer cells, and ZnPc is loaded onto CD-PEG-FA via π-π stacking interactions. CD-PEG-FA/ZnPc exhibits excellent targeted delivery of the PS, leading to simultaneous imaging and significant targeted photodynamic therapy after irradiation in vitro and in vivo. The present CD-based targeted delivery of PSs is anticipated to offer a convenient and effective platform for enhanced photodynamic therapy to treat cancers in the near future. | - |
dc.identifier.bibliographicCitation | ADVANCED FUNCTIONAL MATERIALS, v.24, no.37, pp.5781 - 5789 | - |
dc.identifier.doi | 10.1002/adfm.201400961 | - |
dc.identifier.issn | 1616-301X | - |
dc.identifier.scopusid | 2-s2.0-84941036373 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/5405 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84907702311 | - |
dc.identifier.wosid | 000342794500001 | - |
dc.language | 영어 | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Highly Biocompatible Carbon Nanodots for Simultaneous Bioimaging and Targeted Photodynamic Therapy In Vitro and In Vivo | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary; Chemistry, Physical; Nanoscience & Nanotechnology; Materials Science, Multidisciplinary; Physics, Applied; Physics, Condensed Matter | - |
dc.relation.journalResearchArea | Chemistry; Science & Technology - Other Topics; Materials Science; Physics | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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