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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 9343 | - |
dc.citation.number | 14 | - |
dc.citation.startPage | 9328 | - |
dc.citation.title | JOURNAL OF ORGANIC CHEMISTRY | - |
dc.citation.volume | 86 | - |
dc.contributor.author | Cho, Il Young | - |
dc.contributor.author | Kim, Woo Gyum | - |
dc.contributor.author | Jeon, Ji Hwan | - |
dc.contributor.author | Lee, Jeong Woo | - |
dc.contributor.author | Seo, Jeong Kon | - |
dc.contributor.author | Seo, Jongcheol | - |
dc.contributor.author | Hong, Sung You | - |
dc.date.accessioned | 2023-12-21T15:39:24Z | - |
dc.date.available | 2023-12-21T15:39:24Z | - |
dc.date.created | 2021-07-16 | - |
dc.date.issued | 2021-07 | - |
dc.description.abstract | Ni(COD)(2) -catalyzed cycloaddition reactions to access pyridines have been extensively studied. However, this catalyst typically requires drying procedures and inert-atmosphere techniques for the reactions. Herein, we report operationally simple nickel(0) catalysis to access substituted pyridines from various nitriles and 1,6-diynes without the aid of air-free techniques. The Ni-Xantphos-based catalytic manifold is tolerant to air, moisture, and heat while promoting the [2 + 2 + 2] cycloaddition reactions with high reaction yields and broad substrate scope. In addition, we disclose that not only the steric effect but also the frontier molecular orbital interactions can play a critical role in determining the regiochemical outcome of nickel-catalyzed [2 + 2 + 2] cycloaddition for the synthesis of substituted pyridines. | - |
dc.identifier.bibliographicCitation | JOURNAL OF ORGANIC CHEMISTRY, v.86, no.14, pp.9328 - 9343 | - |
dc.identifier.doi | 10.1021/acs.joc.1c00577 | - |
dc.identifier.issn | 0022-3263 | - |
dc.identifier.scopusid | 2-s2.0-85110959745 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/53254 | - |
dc.identifier.url | https://pubs.acs.org/doi/10.1021/acs.joc.1c00577 | - |
dc.identifier.wosid | 000674931400007 | - |
dc.language | 영어 | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Nickelocene as an Air- and Moisture-Tolerant Precatalyst in the Regioselective Synthesis of Multisubstituted Pyridines | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | CATALYZED 2+2+2 CYCLOADDITIONNICKEL(0) CATALYSTSDIYNESALPHA | - |
dc.subject.keywordPlus | OMEGA-DIYNESNITRILESCYCLIZATION1 | - |
dc.subject.keywordPlus | 6-DIYNESCONSTRUCTIONLIGANDSGENERATION | - |
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