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홍성유

Hong, Sung You
Synthetic Organic Chemistry Lab.
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dc.citation.endPage 9343 -
dc.citation.number 14 -
dc.citation.startPage 9328 -
dc.citation.title JOURNAL OF ORGANIC CHEMISTRY -
dc.citation.volume 86 -
dc.contributor.author Cho, Il Young -
dc.contributor.author Kim, Woo Gyum -
dc.contributor.author Jeon, Ji Hwan -
dc.contributor.author Lee, Jeong Woo -
dc.contributor.author Seo, Jeong Kon -
dc.contributor.author Seo, Jongcheol -
dc.contributor.author Hong, Sung You -
dc.date.accessioned 2023-12-21T15:39:24Z -
dc.date.available 2023-12-21T15:39:24Z -
dc.date.created 2021-07-16 -
dc.date.issued 2021-07 -
dc.description.abstract Ni(COD)(2) -catalyzed cycloaddition reactions to access pyridines have been extensively studied. However, this catalyst typically requires drying procedures and inert-atmosphere techniques for the reactions. Herein, we report operationally simple nickel(0) catalysis to access substituted pyridines from various nitriles and 1,6-diynes without the aid of air-free techniques. The Ni-Xantphos-based catalytic manifold is tolerant to air, moisture, and heat while promoting the [2 + 2 + 2] cycloaddition reactions with high reaction yields and broad substrate scope. In addition, we disclose that not only the steric effect but also the frontier molecular orbital interactions can play a critical role in determining the regiochemical outcome of nickel-catalyzed [2 + 2 + 2] cycloaddition for the synthesis of substituted pyridines. -
dc.identifier.bibliographicCitation JOURNAL OF ORGANIC CHEMISTRY, v.86, no.14, pp.9328 - 9343 -
dc.identifier.doi 10.1021/acs.joc.1c00577 -
dc.identifier.issn 0022-3263 -
dc.identifier.scopusid 2-s2.0-85110959745 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/53254 -
dc.identifier.url https://pubs.acs.org/doi/10.1021/acs.joc.1c00577 -
dc.identifier.wosid 000674931400007 -
dc.language 영어 -
dc.publisher AMER CHEMICAL SOC -
dc.title Nickelocene as an Air- and Moisture-Tolerant Precatalyst in the Regioselective Synthesis of Multisubstituted Pyridines -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.relation.journalWebOfScienceCategory Chemistry, Organic -
dc.relation.journalResearchArea Chemistry -
dc.type.docType Article -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.subject.keywordPlus CATALYZED 2+2+2 CYCLOADDITIONNICKEL(0) CATALYSTSDIYNESALPHA -
dc.subject.keywordPlus OMEGA-DIYNESNITRILESCYCLIZATION1 -
dc.subject.keywordPlus 6-DIYNESCONSTRUCTIONLIGANDSGENERATION -

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