MicroTas : 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, pp.1234 - 1236
Abstract
We demonstrate active directional control of microtubule translocation in microfluidic chambers with E-fields. An E-field produces enough electrophoretic force on the leading end of moving microtubules to bend them towards the anode, such that the entire microtubule quickly aligns with the E-field. With time-varying E-field control, we are able to direct microtubules along arbitrary paths; as an example we direct a microtubule to translocate in a circle about 30 μm in diameter.