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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 2291 | - |
dc.citation.number | 19 | - |
dc.citation.startPage | 2283 | - |
dc.citation.title | CURRENT ORGANIC CHEMISTRY | - |
dc.citation.volume | 24 | - |
dc.contributor.author | Raju, Koppada Masthan | - |
dc.contributor.author | Cheedarala, Ravi Kumar | - |
dc.contributor.author | Pandurangan, Arumugam | - |
dc.date.accessioned | 2023-12-21T16:38:01Z | - |
dc.date.available | 2023-12-21T16:38:01Z | - |
dc.date.created | 2021-02-03 | - |
dc.date.issued | 2020-12 | - |
dc.description.abstract | A simple, efficient, and cheap strategy has been developed for N-arylation of indoles with hexafloro benzene (1) via incorporating sulfolane as an eco-friendly solvent. N-Monopentafluoroarylindole (3) at ambient conditions and N, N-bistetrafluomaryl indole (4) at elevated temperatures were conveniently obtained by simple nucleophilic substitution using NaOH as the base and sulfolane as a reaction medium to obtain in moderately good yields, respectively. Subsequently, 3-chloro, 3-bromo, and 3-iodomono-pentafluoroarylindoles and 3, 3'-dichloro, 3, 3'-dibromo and 3, 3'-dilodobistetrafluoroaryl indoles were prepared in good yields by using respective halogenating reagents and solvents. All the chemical transformations were confirmed by analytical tools such as 1HNMR, FR-IR and HRMS analysis. | - |
dc.identifier.bibliographicCitation | CURRENT ORGANIC CHEMISTRY, v.24, no.19, pp.2283 - 2291 | - |
dc.identifier.doi | 10.2174/1385272824999200914111909 | - |
dc.identifier.issn | 1385-2728 | - |
dc.identifier.scopusid | 2-s2.0-85095729162 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/49941 | - |
dc.identifier.url | https://www.eurekaselect.com/185883/article | - |
dc.identifier.wosid | 000595626400006 | - |
dc.language | 영어 | - |
dc.publisher | BENTHAM SCIENCE PUBL LTD | - |
dc.title | Sulfolane Mediated Highly Selective Synthesis of Mono and Bis-aryl-2-Methyl-6-Fluoro-Indoles and Their Halogenated Synthons | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | 2-Methyl-6-fluoro-indole | - |
dc.subject.keywordAuthor | hexafluorobezene | - |
dc.subject.keywordAuthor | indole derivative | - |
dc.subject.keywordAuthor | mono fluoroaryl indoles and bisfluoroaryl indoles | - |
dc.subject.keywordAuthor | nucleophilic substitution | - |
dc.subject.keywordAuthor | (HNMR)-H-1 | - |
dc.subject.keywordPlus | N-ARYLATION | - |
dc.subject.keywordPlus | RECEPTOR | - |
dc.subject.keywordPlus | INDOLES | - |
dc.subject.keywordPlus | DOPAMINE-D-2 | - |
dc.subject.keywordPlus | ANTAGONISTS | - |
dc.subject.keywordPlus | ACETATE | - |
dc.subject.keywordPlus | SERIES | - |
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