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박성훈

Park, Sunghoon
Biochemical Engineering Lab.
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dc.citation.startPage 500867 -
dc.citation.title FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY -
dc.citation.volume 8 -
dc.contributor.author Nasir, Abdul -
dc.contributor.author Ashok, Somasundar -
dc.contributor.author Shim, Jeung Yeop -
dc.contributor.author Park, Sunghoon -
dc.contributor.author Yoo, Tae Hyeon -
dc.date.accessioned 2023-12-21T16:42:46Z -
dc.date.available 2023-12-21T16:42:46Z -
dc.date.created 2020-12-08 -
dc.date.issued 2020-11 -
dc.description.abstract Coenzyme B-12-dependent glycerol dehydratase (GDHt) catalyzes the dehydration reaction of glycerol in the presence of adenosylcobalamin to yield 3-hydroxypropanal (3-HPA), which can be converted biologically to versatile platform chemicals such as 1,3-propanediol and 3-hydroxypropionic acid. Owing to the increased demand for biofuels, developing biological processes based on glycerol, which is a byproduct of biodiesel production, has attracted considerable attention recently. In this review, we will provide updates on the current understanding of the catalytic mechanism and structure of coenzyme B-12-dependent GDHt, and then summarize the results of engineering attempts, with perspectives on future directions in its engineering. -
dc.identifier.bibliographicCitation FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, v.8, pp.500867 -
dc.identifier.doi 10.3389/fbioe.2020.500867 -
dc.identifier.issn 2296-4185 -
dc.identifier.scopusid 2-s2.0-85096237393 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/49294 -
dc.identifier.url https://www.frontiersin.org/articles/10.3389/fbioe.2020.500867/full -
dc.identifier.wosid 000590267400001 -
dc.language 영어 -
dc.publisher FRONTIERS MEDIA SA -
dc.title Recent Progress in the Understanding and Engineering of Coenzyme B-12-Dependent Glycerol Dehydratase -
dc.type Article -
dc.description.isOpenAccess TRUE -
dc.relation.journalWebOfScienceCategory Biotechnology & Applied Microbiology; Multidisciplinary Sciences -
dc.relation.journalResearchArea Biotechnology & Applied Microbiology; Science & Technology - Other Topics -
dc.type.docType Review -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.subject.keywordAuthor glycerol dehydratase -
dc.subject.keywordAuthor coenzyme B-12 -
dc.subject.keywordAuthor glycerol -
dc.subject.keywordAuthor inactivation -
dc.subject.keywordAuthor reactivase -
dc.subject.keywordAuthor enzyme engineering -
dc.subject.keywordPlus DEPENDENT DIOL DEHYDRASE -
dc.subject.keywordPlus KLEBSIELLA-PNEUMONIAE -
dc.subject.keywordPlus RADICAL CATALYSIS -
dc.subject.keywordPlus CRYSTAL-STRUCTURE -
dc.subject.keywordPlus SATURATION-MUTAGENESIS -
dc.subject.keywordPlus SUBSTRATE-SPECIFICITY -
dc.subject.keywordPlus BIODIESEL PRODUCTION -
dc.subject.keywordPlus MECHANISM -
dc.subject.keywordPlus ENZYMES -
dc.subject.keywordPlus ADENOSYLCOBALAMIN -

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