Full metadata record
DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 43388 | - |
dc.citation.number | 71 | - |
dc.citation.startPage | 43383 | - |
dc.citation.title | RSC Advances | - |
dc.citation.volume | 10 | - |
dc.contributor.author | Kim, Sangpil | - |
dc.contributor.author | Kim, Juhee | - |
dc.contributor.author | Jana, Batakrishna | - |
dc.contributor.author | Ryu, Ja-Hyoung | - |
dc.date.accessioned | 2023-12-21T16:38:49Z | - |
dc.date.available | 2023-12-21T16:38:49Z | - |
dc.date.created | 2020-12-22 | - |
dc.date.issued | 2020-12 | - |
dc.description.abstract | Controlled intracellular chemical reactions to regulate cellular functions remain a challenge in biology mimetic systems. Herein, we developed an intra-mitochondrial bio-orthogonal reaction to induce aggregation induced emission. In situ carbonyl ligation inside mitochondria drives the molecules to form nano-aggregates with green fluorescence, which leads to depolarization of the mitochondrial membrane, generation of ROS, and subsequently mitochondrial dysfunction. This intra-mitochondrial carbonyl ligation shows great potential for anticancer treatment in various cancer cell lines. | - |
dc.identifier.bibliographicCitation | RSC Advances, v.10, no.71, pp.43383 - 43388 | - |
dc.identifier.doi | 10.1039/d0ra07471c | - |
dc.identifier.issn | 2046-2069 | - |
dc.identifier.scopusid | 2-s2.0-85097948989 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/48991 | - |
dc.identifier.url | https://pubs.rsc.org/en/content/articlelanding/2020/RA/D0RA07471C#!divAbstract | - |
dc.identifier.wosid | 000599464100015 | - |
dc.language | 영어 | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Intra-mitochondrial reaction for cancer cell imaging and anti-cancer therapy by aggregation-induced emission | - |
dc.type | Article | - |
dc.description.isOpenAccess | TRUE | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | PROBE | - |
dc.subject.keywordPlus | DELIVERY | - |
dc.subject.keywordPlus | SYSTEMS | - |
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