dc.citation.endPage |
73 |
- |
dc.citation.number |
1 |
- |
dc.citation.startPage |
68 |
- |
dc.citation.title |
ADVANCES IN BIOLOGICAL REGULATION |
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dc.citation.volume |
54 |
- |
dc.contributor.author |
Yang, Yong Ryoul |
- |
dc.contributor.author |
Suh, Pann-Ghill |
- |
dc.date.accessioned |
2023-12-22T03:08:37Z |
- |
dc.date.available |
2023-12-22T03:08:37Z |
- |
dc.date.created |
2014-02-20 |
- |
dc.date.issued |
2014-01 |
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dc.description.abstract |
O-GlcNAcylation is dynamic and a ubiquitous post-translational modification. O-GlcNAcylated proteins influence fundamental functions of proteins such as protein-protein interactions, altering protein stability, and changing protein activity. Thus, aberrant regulation of O-GlcNAcylation contributes to the etiology of chronic diseases of aging, including cancer, cardiovascular disease, metabolic disorders, and Alzheimer's disease. Diverse cellular signaling systems are involved in pathogenesis of these diseases. O-GlcNAcylated proteins occur in many different tissues and cellular compartments and affect specific cell signaling. This review focuses on the O-GlcNAcylation in basic cellular functions and human diseases. |
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dc.identifier.bibliographicCitation |
ADVANCES IN BIOLOGICAL REGULATION, v.54, no.1, pp.68 - 73 |
- |
dc.identifier.doi |
10.1016/j.jbior.2013.09.007 |
- |
dc.identifier.issn |
2212-4926 |
- |
dc.identifier.scopusid |
2-s2.0-84893408121 |
- |
dc.identifier.uri |
https://scholarworks.unist.ac.kr/handle/201301/4227 |
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dc.language |
영어 |
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dc.publisher |
ELSEVIER BV |
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dc.title |
O-GlcNAcylation in cellular functions and human diseases |
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dc.type |
Article |
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dc.description.journalRegisteredClass |
scopus |
- |