dc.citation.conferencePlace |
KO |
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dc.citation.conferencePlace |
일산 |
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dc.citation.title |
115th Annual Meeting of Korean Chemical Society |
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dc.contributor.author |
Yang, Seongho |
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dc.contributor.author |
Ryu, Ja-Hyoung |
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dc.contributor.author |
Choi, Insung |
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dc.date.accessioned |
2023-12-19T22:38:41Z |
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dc.date.available |
2023-12-19T22:38:41Z |
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dc.date.created |
2016-01-05 |
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dc.date.issued |
2015-04-15 |
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dc.description.abstract |
Layer-by-layer (LbL) assembly has recently emerged as a highly versatile and promising method for biochemical and biomedical applications. Accordingly, it is urgently necessary to develop a cytocompatible LbL assembly technique that is stable and offers on-demand degradation and functionalization. In this study, we developed a simple and biocompatible LbL technique that cross-links the layers through covalent bonds under physiological conditions without requirement of any post-treatments or additives. By utilizing the dynamic nature of the disulfide bond, stable LbL films can be spontaneously formed during the process, further functionalized using thiol-maleimide chemistry, and degraded in response to glutathione. In addition, we demonstrated that the method is applicable to plate surfaces, spherical nanoparticles, and even living cells. |
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dc.identifier.bibliographicCitation |
115th Annual Meeting of Korean Chemical Society |
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dc.identifier.uri |
https://scholarworks.unist.ac.kr/handle/201301/42178 |
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dc.identifier.url |
https://kcsnet.or.kr/?mid=abstract_view&uid=30025&page=37&wordfield=partnum&main_number=115 |
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dc.language |
영어 |
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dc.publisher |
대한화학회 |
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dc.title |
Cross-linkable and Degradable Layer-by-Layer Assembly under Cytocompatible Conditions for Cell-Encapsulation |
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dc.type |
Conference Paper |
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dc.date.conferenceDate |
2015-04-15 |
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