Present technology and future trends in point-of-care micro fluidic diagnostics
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- Present technology and future trends in point-of-care micro fluidic diagnostics
- Kulinsky, Lawrence; Noroozi, Zahra; Madou, Mark
- Diagnostics; Immunoassay; Lateral flow; Micro fluidics; Molecular diagnostics; POC; POCT; Point of care
- Issue Date
- HUMANA PRESS INC
- METHODS IN MOLECULAR BIOLOGY, v.949, no., pp.3 - 23
- This work reviews present technologies and developing trends in Point-of-Care (POC) micro fluidic diagnostics platforms. First, various fluidics technologies such as pressure-driven flows, capillary flows, electromagnetically driven flows, centrifugal fluidics, acoustically driven flows, and droplet fluidics are categorized. Then three broad categories of POC micro fluidic testing devices are considered: lateral flow devices, desktop and handheld POC diagnostic platforms, and emergent molecular diagnostic POC systems. Such evolving trends as miniaturization, multiplexing, networking, new more sensitive detection schemes, and the importance of sample processing are discussed. It is concluded that POC micro fluidic diagnostics has a potential to improve patient treatment outcome and bring substantial savings in overall healthcare costs.
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