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GrzybowskiBartosz Andrzej

Grzybowski, Bartosz A.
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dc.citation.endPage 679 -
dc.citation.number 6 -
dc.citation.startPage 672 -
dc.citation.title SOFT MATTER -
dc.citation.volume 3 -
dc.contributor.author Kandere-Grzybowska, Kristiana -
dc.contributor.author Campbell, Christopher J. -
dc.contributor.author Mahmud, Goher -
dc.contributor.author Komarova, Yulia -
dc.contributor.author Soh, Siowling -
dc.contributor.author Grzybowski, Bartosz A. -
dc.date.accessioned 2023-12-22T09:37:52Z -
dc.date.available 2023-12-22T09:37:52Z -
dc.date.created 2020-07-14 -
dc.date.issued 2007 -
dc.description.abstract Surfaces micropatterned with disjointed cell adhesive/non-adhesive regions allow for precise control of cell shape, internal organization and function. In particular, substrates prepared by the reaction - diffusion ASoMic ( Anisotropic So lid Microetching) method localize cells onto transparent micro-islands or tracks surrounded by an opaque, adhesion-resistant background. ASoMic is compatible with several important imaging modalities ( e. g. wide-field, fluorescent, TIRF and confocal microscopies), and can be used to study and quantify various intracellular and cellular processes related to cell motility. For cells constrained on the islands, the imposed geometry controls spatial organization of the cytoskeleton, while the transparency of the islands allows for real-time analysis of cytoskeletal dynamics. For cells on transparent, linear tracks, the high optical contrast between these adhesive regions and the surrounding non-adhesive background allows for straightforward quantification of the key parameters describing cell motility. Both types of systems provide analytical-quality data that can assist fundamental studies of cell locomotion and can provide a technological basis for cell motility microassays. -
dc.identifier.bibliographicCitation SOFT MATTER, v.3, no.6, pp.672 - 679 -
dc.identifier.doi 10.1039/b617308j -
dc.identifier.issn 1744-683X -
dc.identifier.scopusid 2-s2.0-34249042008 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/33368 -
dc.identifier.url https://pubs.rsc.org/en/content/articlelanding/2007/SM/b617308j#!divAbstract -
dc.identifier.wosid 000246696700002 -
dc.language 영어 -
dc.publisher ROYAL SOC CHEMISTRY -
dc.title Cell motility on micropatterned treadmills and tracks -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.relation.journalWebOfScienceCategory Chemistry, Physical; Materials Science, Multidisciplinary; Physics, Multidisciplinary; Polymer Science -
dc.relation.journalResearchArea Chemistry; Materials Science; Physics; Polymer Science -
dc.type.docType Article -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.subject.keywordPlus MIGRATION -
dc.subject.keywordPlus GROWTH -
dc.subject.keywordPlus SHAPE -
dc.subject.keywordPlus FIBROBLASTS -
dc.subject.keywordPlus SURFACES -
dc.subject.keywordPlus MICROTUBULES -
dc.subject.keywordPlus ORIENTATION -
dc.subject.keywordPlus ADHESIONS -
dc.subject.keywordPlus SIGNALS -
dc.subject.keywordPlus ASSAY -

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