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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 661 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 652 | - |
dc.citation.title | BIOPHYSICAL JOURNAL | - |
dc.citation.volume | 78 | - |
dc.contributor.author | Grzybowski, BA | - |
dc.contributor.author | Anderson, JR | - |
dc.contributor.author | Colton, I | - |
dc.contributor.author | Brittain, ST | - |
dc.contributor.author | Shakhnovich, EI | - |
dc.contributor.author | Whitesides, GM | - |
dc.date.accessioned | 2023-12-22T12:08:20Z | - |
dc.date.available | 2023-12-22T12:08:20Z | - |
dc.date.created | 2020-07-14 | - |
dc.date.issued | 2000-02 | - |
dc.description.abstract | This paper describes a theoretical method for solving systems of coupled differential equations that describe the kinetics of complicated reaction networks in which a molecule having multiple reaction sites reacts irreversibly with multiple equivalents of a ligand (reagent). The members of the network differ in the number of equivalents of reagent that have reacted, and in the patterns of sites of reaction. A recursive algorithm generates series, asymptotic, and average solutions describing this kinetic scheme. This method was validated by successfully simulating the experimental data for the kinetics of acylation of insulin. | - |
dc.identifier.bibliographicCitation | BIOPHYSICAL JOURNAL, v.78, no.2, pp.652 - 661 | - |
dc.identifier.doi | 10.1016/S0006-3495(00)76623-9 | - |
dc.identifier.issn | 0006-3495 | - |
dc.identifier.scopusid | 2-s2.0-0034036856 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/33317 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0006349500766239?via%3Dihub | - |
dc.identifier.wosid | 000085249300009 | - |
dc.language | 영어 | - |
dc.publisher | BIOPHYSICAL SOCIETY | - |
dc.title | Modeling the kinetics of acylation of insulin using a recursive method for solving the systems of coupled differential equations | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | PROTEIN CHARGE LADDERS | - |
dc.subject.keywordPlus | CAPILLARY ELECTROPHORESIS | - |
dc.subject.keywordPlus | BINDING | - |
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