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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 8784 | - |
dc.citation.number | 21 | - |
dc.citation.startPage | 8780 | - |
dc.citation.title | ANALYTICAL CHEMISTRY | - |
dc.citation.volume | 82 | - |
dc.contributor.author | Wei, Yanhu | - |
dc.contributor.author | Wesson, Paul J. | - |
dc.contributor.author | Kourkine, Igor | - |
dc.contributor.author | Grzybowski, Bartosz A. | - |
dc.date.accessioned | 2023-12-22T06:39:51Z | - |
dc.date.available | 2023-12-22T06:39:51Z | - |
dc.date.created | 2020-07-14 | - |
dc.date.issued | 2010-11 | - |
dc.description.abstract | Protein-ligand dissociation constants, lid, are determined precisely and down to the picomolar range from reaction-diffusion (RI)) concentration profiles created by proteins diffusing through hydrogels functionalized with protein ligands. The RD process effectively amplifies the molecular-scale binding events into macroscopic patterns visible to the naked eye. The method is applicable to various protein-ligand pairs and does not require any prior knowledge about the protein structure. | - |
dc.identifier.bibliographicCitation | ANALYTICAL CHEMISTRY, v.82, no.21, pp.8780 - 8784 | - |
dc.identifier.doi | 10.1021/ac102055a | - |
dc.identifier.issn | 0003-2700 | - |
dc.identifier.scopusid | 2-s2.0-78049507580 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/33219 | - |
dc.identifier.url | https://pubs.acs.org/doi/10.1021/ac102055a | - |
dc.identifier.wosid | 000283531200006 | - |
dc.language | 영어 | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Measurement of Protein-Ligand Binding Constants from Reaction-Diffusion Concentration Profiles | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | HUMAN-SERUM-ALBUMIN | - |
dc.subject.keywordPlus | PERFORMANCE AFFINITY-CHROMATOGRAPHY | - |
dc.subject.keywordPlus | ISOTHERMAL TITRATION CALORIMETRY | - |
dc.subject.keywordPlus | SURFACE-PLASMON RESONANCE | - |
dc.subject.keywordPlus | MASS-SPECTROMETRY | - |
dc.subject.keywordPlus | EQUILIBRIUM DIALYSIS | - |
dc.subject.keywordPlus | CARBONIC-ANHYDRASE | - |
dc.subject.keywordPlus | CIRCULAR-DICHROISM | - |
dc.subject.keywordPlus | NMR | - |
dc.subject.keywordPlus | ULTRAFILTRATION | - |
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