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Takayama, Shuichi
Cell and Microfluidics Lab
Research Interests
  • Bio-MEMS and Microfluidics
  • Bio-Nanotechnology
  • Biofluids
  • Biomaterials
  • Tissue Engineering and Regenerative Medicine.


Lab-on-a-chip biophotonics: its application to assisted reproductive technologies

DC Field Value Language Lai, David ko Smith, Gary D. ko Takayama, Shuichi ko 2014-04-10T01:43:22Z - 2013-06-21 ko 2012-08 -
dc.identifier.citation JOURNAL OF BIOPHOTONICS, v.5, no.8-9, pp.650 - 660 ko
dc.identifier.issn 1864-063X ko
dc.identifier.uri -
dc.identifier.uri ko
dc.description.abstract With the benefits of automation, sensitivity and precision, microfluidics has enabled complex and otherwise tedious experiments. Lately, lab-on-a-chip (LOC) has proven to be a useful tool for enhancing non-invasive assisted reproductive technology (ART). Non-invasive gamete and embryo assessment has largely been through periodic morpohological assessment using optical microscopy and early LOC ART was the same. As we realize that morphological assessment is a poor indication of gamete or embryo health, more advanced biophotonics has emerged in LOC ART to assay for metabolites or gamete separation via optoelectrical tweezers. Off-chip, even more advanced biophotonics with broad spectrum analysis of metabolites and secretomes has been developed that show even higher accuracy to predicting reproductive potential. The integration of broad spectrum metabolite analysis into LOC ART is an exciting future that merges automation and sensitivity with the already highly accurate and strong predictive power of biophotonics ko
dc.description.statementofresponsibility close -
dc.language ENG ko
dc.publisher WILEY-V C H VERLAG GMBH ko
dc.subject Assisted reproductive technologies ko
dc.subject Bio photonics ko
dc.subject Broad spectrum ko
dc.subject Lab on a chip ko
dc.subject Metabolite analysis ko
dc.subject Off-chip ko
dc.subject Optoelectrical ko
dc.subject Predictive power ko
dc.subject Reproductive potential ko
dc.title Lab-on-a-chip biophotonics: its application to assisted reproductive technologies ko
dc.type ARTICLE ko
dc.identifier.scopusid 2-s2.0-84864526079 ko
dc.identifier.wosid 000307016600010 ko
dc.type.rims ART ko
dc.description.scopustc 4 * 2014-07-12 *
dc.identifier.doi 10.1002/jbio.201200041 ko
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