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이성국

Lee, Sung Kuk
Synthetic Biology & Metabolic Engineering Lab.
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dc.citation.endPage 6 -
dc.citation.number 9 -
dc.citation.startPage 1 -
dc.citation.title JOURNAL OF MICROMECHANICS AND MICROENGINEERING -
dc.citation.volume 20 -
dc.contributor.author Kim, Sang Yub -
dc.contributor.author Lee, Eun Se -
dc.contributor.author Lee, Ho Jae -
dc.contributor.author Lee, Se Yeon -
dc.contributor.author Lee, Sung Kuk -
dc.contributor.author Kim, Taesung -
dc.date.accessioned 2023-12-22T06:45:19Z -
dc.date.available 2023-12-22T06:45:19Z -
dc.date.created 2013-06-12 -
dc.date.issued 2010-09 -
dc.description.abstract We present a novel microfabricated concentrator for Escherichia coli that can be a stand-alone and self-contained microfluidic device because it utilizes the motility of cells. First of all, we characterize the motility of E. coli cells and various ratcheting structures that can guide cells to move in a desired direction in straight and circular channels. Then, we combine these ratcheting microstructures with the intrinsic tendency of cells to swim on the right side in microchannels to enhance the concentration rates up to 180 fold until the concentrators are fully filled with cells. Furthermore, we demonstrate that cells can be positioned and concentrated with a constant spacing distance on a surface, allowing spatial patterning of motile cells. These results can be applied to biosorption or biosensor devices that are powered by motile cells because they can be highly concentrated without any external mechanical and electrical energy sources. Hence, we believe that the concentrator design holds considerable potential to be applied for concentrating and patterning other motile microbes and providing a versatile structure for motility study of bacterial cells. -
dc.identifier.bibliographicCitation JOURNAL OF MICROMECHANICS AND MICROENGINEERING, v.20, no.9, pp.1 - 6 -
dc.identifier.doi 10.1088/0960-1317/20/9/095006 -
dc.identifier.issn 0960-1317 -
dc.identifier.scopusid 2-s2.0-77957792983 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/3141 -
dc.identifier.url http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=77957792983 -
dc.identifier.wosid 000281398800006 -
dc.language 영어 -
dc.publisher IOP PUBLISHING LTD -
dc.title Microfabricated ratchet structures for concentrating and patterning motile bacterial cells -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.relation.journalWebOfScienceCategory Engineering, Electrical & Electronic; Nanoscience & Nanotechnology; Instruments & Instrumentation; Physics, Applied -
dc.relation.journalResearchArea Engineering; Science & Technology - Other Topics; Instruments & Instrumentation; Physics -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -

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