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DC Field | Value | Language |
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dc.citation.endPage | 11592 | - |
dc.citation.number | 18 | - |
dc.citation.startPage | 11589 | - |
dc.citation.title | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | - |
dc.citation.volume | 99 | - |
dc.contributor.author | Bar-Ziv, R | - |
dc.contributor.author | Tlusty, T | - |
dc.contributor.author | Libchaber, A | - |
dc.date.accessioned | 2023-12-22T11:36:56Z | - |
dc.date.available | 2023-12-22T11:36:56Z | - |
dc.date.created | 2020-02-20 | - |
dc.date.issued | 2002-09 | - |
dc.description.abstract | The assembly of RecA on single-stranded DNA is measured and interpreted as a stochastic finite-state machine that is able to discriminate fine differences between sequences, a basic computational operation. RecA filaments efficiently scan DNA sequence through a cascade of random nucleation and disassembly events that is mechanistically similar to the dynamic instability of microtubules. This iterative cascade is a multistage kinetic proofreading process that amplifies minute differences, even a single base change. Our measurements suggest that this stochastic Turing-like machine can compute certain integral transforms. | - |
dc.identifier.bibliographicCitation | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, v.99, no.18, pp.11589 - 11592 | - |
dc.identifier.doi | 10.1073/pnas.162369099 | - |
dc.identifier.issn | 0027-8424 | - |
dc.identifier.scopusid | 2-s2.0-0037015031 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/31213 | - |
dc.identifier.url | https://www.pnas.org/content/99/18/11589 | - |
dc.identifier.wosid | 000177843100013 | - |
dc.language | 영어 | - |
dc.publisher | NATL ACAD SCIENCES | - |
dc.title | Protein-DNA computation by stochastic assembly cascade | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | RECA | - |
dc.subject.keywordPlus | FILAMENTS | - |
dc.subject.keywordPlus | EVOLUTION | - |
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