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Kim, Gun-Ho
SoftHeat Group
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  • Heat transfer mechanism in soft materials (e.g., plastics, animal tissues)

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Low cost synthesis of reduced graphene oxide using biopolymer for influenza virus sensor

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Title
Low cost synthesis of reduced graphene oxide using biopolymer for influenza virus sensor
Author
Joshi, Shalik R.Sharma, AbhinavKim, Gun-HoJang, Jaesung
Issue Date
2020-03
Publisher
Elsevier BV
Citation
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, v.108, pp.110465
Abstract
A biocompatible, cost-effective, and scalable reduced graphene oxide (rGO) film was obtained from shellac using thermal treatment and its structural, chemical, and electrical properties were investigated. This thermally-decomposed rGO (TrGO) film exhibited good crystallinity, low sheet resistance, and high carbon content. TrGO flakes obtained from the film were dispersed and drop cast onto indium tin oxide/glass electrodes to fabricate label-free electrochemical immunosensors for the quantitative detection of the influenza virus H1N1 via electrochemical impedance spectroscopy. These sensors exhibited high stability and reproducibility, both possibly ascribable to the high adhesion of TrGO due to its phenolic-OH moiety; the limits of detection were 26 and 33 plaque-forming units, respectively, in phosphate-buffered saline and diluted saliva. These cost-effective TrGO-based sensors showed great potential as reliable and robust nanomaterial-based biosensors for widespread clinical applications.
URI
https://scholarworks.unist.ac.kr/handle/201301/30477
URL
https://www.sciencedirect.com/science/article/pii/S0928493119332461?via%3Dihub
DOI
10.1016/j.msec.2019.110465
ISSN
0928-4931
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