Full metadata record
DC Field | Value | Language |
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dc.citation.number | 2 | - |
dc.citation.startPage | 224 | - |
dc.citation.title | NANOMATERIALS | - |
dc.citation.volume | 9 | - |
dc.contributor.author | Lee, Sanghwa | - |
dc.contributor.author | Namgoong, Jung-Man | - |
dc.contributor.author | Yu, Hwan Yeul | - |
dc.contributor.author | Jue, Miyeon | - |
dc.contributor.author | Kim, Gwanho | - |
dc.contributor.author | Jeon, Sangmin | - |
dc.contributor.author | Shin, Dong-Myung | - |
dc.contributor.author | Choo, Myung-Soo | - |
dc.contributor.author | Joo, Jinmyoung | - |
dc.contributor.author | Pack, Chan-Gi | - |
dc.contributor.author | Kim, Jun Ki | - |
dc.date.accessioned | 2023-12-21T19:37:15Z | - |
dc.date.available | 2023-12-21T19:37:15Z | - |
dc.date.created | 2019-03-28 | - |
dc.date.issued | 2019-02 | - |
dc.description.abstract | To evaluate the feasibility of ZnO nanorod-based surface enhanced Raman scattering (SERS) diagnostics for disease models, particularly for interstitial cystitis/bladder pain syndrome (IC/BPS), ZnO-based SERS sensing chips were developed and applied to an animal disease model. ZnO nanorods were grown to form nano-sized porous structures and coated with gold to facilitate size-selective biomarker detection. Raman spectra were acquired on a surface enhanced Raman substrate from the urine in a rat model of IC/BPS and analyzed using a statistical analysis method called principal component analysis (PCA). The nanorods grown after the ZnO seed deposition were 30 to 50 nm in diameter and 500 to 600 nm in length. A volume of gold corresponding to a thin film thickness of 100 nm was deposited on the grown nanorod structure. Raman spectroscopic signals were measured in the scattered region for nanometer biomarker detection to indicate IC/BPS. The Raman peaks for the control group and IC/BPS group are observed at 641, 683, 723, 873, 1002, 1030, and 1355 cm(-1),which corresponded to various bonding types and compounds. The PCA results are plotted in 2D and 3D. The Raman signals and statistical analyses obtained from the nano-sized biomarkers of intractable inflammatory diseases demonstrate the possibility of an early diagnosis. | - |
dc.identifier.bibliographicCitation | NANOMATERIALS, v.9, no.2, pp.224 | - |
dc.identifier.doi | 10.3390/nano9020224 | - |
dc.identifier.issn | 2079-4991 | - |
dc.identifier.scopusid | 2-s2.0-85071018590 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/30424 | - |
dc.identifier.url | https://www.mdpi.com/2079-4991/9/2/224 | - |
dc.identifier.wosid | 000460806700093 | - |
dc.language | 영어 | - |
dc.publisher | MDPI | - |
dc.title | Diagnosis in a Preclinical Model of Bladder Pain Syndrome Using a Au/ZnO Nanorod-based SERS Substrate | - |
dc.type | Article | - |
dc.description.isOpenAccess | TRUE | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology; Materials Science, Multidisciplinary | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics; Materials Science | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | interstitial cystitis/bladder pain syndrome (IC/BPS) | - |
dc.subject.keywordAuthor | ZnO nanorods | - |
dc.subject.keywordAuthor | surface enhancement Raman spectroscopy (SERS) | - |
dc.subject.keywordAuthor | principal component analysis (PCA) | - |
dc.subject.keywordPlus | MICRO-RAMAN SPECTROSCOPY | - |
dc.subject.keywordPlus | ZNO NANORODS | - |
dc.subject.keywordPlus | CYSTITIS | - |
dc.subject.keywordPlus | EXOSOMES | - |
dc.subject.keywordPlus | GROWTH | - |
dc.subject.keywordPlus | CANCER | - |
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