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Park, Jung-Hoon
Bio-Optics Lab
Research Interests
  • Biomedical optics, wavefront shaping, In-vivo deep tissue imaging

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Overcoming the penetration depth limit in optical microscopy: Adaptive optics and wavefront shaping

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Title
Overcoming the penetration depth limit in optical microscopy: Adaptive optics and wavefront shaping
Author
Ahn, CheolwooHwang, ByungjaeNam, KibumJin, HyungwonWoo, TaeseongPark, Jung-Hoon
Issue Date
2019-07
Publisher
World Scientific Publishing Co. Pte Ltd
Citation
JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, v.12, no.04, pp.1930002
Abstract
Despite the unique advantages of optical microscopy for molecular specific high resolution imaging of living structure in both space and time, current applications are mostly limited to research settings. This is due to the aberrations and multiple scattering that is induced by the inhomogeneous refractive boundaries that are inherent to biological systems. However, recent developments in adaptive optics and wavefront shaping have shown that high resolution optical imaging is not fundamentally limited only to the observation of single cells, but can be significantly enhanced to realize deep tissue imaging. To provide insight into how these two closely related fields can expand the limits of bio imaging, we review the recent progresses in their performance and applicable range of studies as well as potential future research directions to push the limits of deep tissue imaging.
URI
https://scholarworks.unist.ac.kr/handle/201301/27479
URL
https://www.worldscientific.com/doi/full/10.1142/S1793545819300027
DOI
10.1142/S1793545819300027
ISSN
1793-5458
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BME_Journal Papers
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