File Download

There are no files associated with this item.

  • Find it @ UNIST can give you direct access to the published full text of this article. (UNISTARs only)
Related Researcher


Lee, Sung Kuk
Synthetic Biology & Metabolic Engineering Lab.
Read More

Views & Downloads

Detailed Information

Cited time in webofscience Cited time in scopus
Metadata Downloads

Full metadata record

DC Field Value Language
dc.citation.endPage 40 -
dc.citation.number 1 -
dc.citation.startPage 23 -
dc.citation.volume 24 - Sathesh-Prabu, Chandran - Shin, Kwang Soo - Kwak, Geun Hwa - Jung, Sang-Kyu - Lee, Sung Kuk - 2023-12-21T19:37:44Z - 2023-12-21T19:37:44Z - 2019-03-07 - 2019-02 -
dc.description.abstract The microbial production of free fatty acids (FFAs) has gained great attention from the scientific community due to its significant environmental and economic benefits. FFAs can also be used as precursors for the production of valuable products, polymer additives and industrial chemicals by various biological or chemical reactions. Since microorganisms synthesize fatty acids (FAs) which are mainly used to form lipids for cell membrane constitution, FFAs are not normally accumulated as metabolic intermediates. FA metabolism is tightly regulated at transcriptional and post-transcriptional levels by both the transcription factor and product inhibition, meaning that FA overproduction may require extensive re-engineering of cellular metabolism. Therefore, we here present the recent efforts applied to enhance FFA production via metabolic engineering and synthetic biology with special reference to Escherichia coli. -
dc.identifier.bibliographicCitation BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, v.24, no.1, pp.23 - 40 -
dc.identifier.doi 10.1007/s12257-018-0374-6 -
dc.identifier.issn 1226-8372 -
dc.identifier.scopusid 2-s2.0-85061227291 -
dc.identifier.uri -
dc.identifier.url -
dc.identifier.wosid 000461396500005 -
dc.language 영어 -
dc.publisher Korean Society for Biotechnology and Bioengineering -
dc.title Microbial Production of Fatty Acid via Metabolic Engineering and Synthetic Biology -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.relation.journalWebOfScienceCategory Biotechnology & Applied Microbiology -
dc.relation.journalResearchArea Biotechnology & Applied Microbiology -
dc.type.docType Article -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.description.journalRegisteredClass kci -
dc.subject.keywordAuthor Escherichia coli -
dc.subject.keywordAuthor fatty acid metabolism -
dc.subject.keywordAuthor metabolic engineering -
dc.subject.keywordAuthor synthetic biology -
dc.subject.keywordPlus Metabolic intermediates -
dc.subject.keywordPlus Microbial production -
dc.subject.keywordPlus Post-transcriptional -
dc.subject.keywordPlus Product inhibition -
dc.subject.keywordPlus Scientific community -
dc.subject.keywordPlus Fatty acids -
dc.subject.keywordPlus Additives -
dc.subject.keywordPlus Cytology -
dc.subject.keywordPlus Economics -
dc.subject.keywordPlus Escherichia coli -
dc.subject.keywordPlus Indicators (chemical) -
dc.subject.keywordPlus Industrial chemicals -
dc.subject.keywordPlus Metabolic engineering -
dc.subject.keywordPlus Metabolism -
dc.subject.keywordPlus Physiology -
dc.subject.keywordPlus Synthetic biology -
dc.subject.keywordPlus Cellular metabolism -
dc.subject.keywordPlus Economic benefits -
dc.subject.keywordPlus Fatty acid metabolism -


Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.