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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 3754 | - |
dc.citation.number | 18 | - |
dc.citation.startPage | 3747 | - |
dc.citation.title | LAB ON A CHIP | - |
dc.citation.volume | 13 | - |
dc.contributor.author | Kim, Tae-Hyeong | - |
dc.contributor.author | Abi-Samra, Kameel | - |
dc.contributor.author | Sunkara, Vijaya | - |
dc.contributor.author | Park, Dong-Kyu | - |
dc.contributor.author | Amasia, Mary | - |
dc.contributor.author | Kim, Nahui | - |
dc.contributor.author | Kim, Jintae | - |
dc.contributor.author | Kim, Hanshin | - |
dc.contributor.author | Madou, Mark | - |
dc.contributor.author | Cho, Yoon-Kyoung | - |
dc.date.accessioned | 2023-12-22T03:38:19Z | - |
dc.date.available | 2023-12-22T03:38:19Z | - |
dc.date.created | 2013-09-03 | - |
dc.date.issued | 2013-09 | - |
dc.description.abstract | We present a novel fully integrated centrifugal microfluidic device with features for target antigen capture from biological samples, via a bead-based enzyme-linked immune-sorbent assay, and flow-enhanced electrochemical detection. The limit of detection (LOD) of our device for the C-reactive protein (CRP) was determined to be 4.9 pg mL-1, a 17-fold improvement over quantification by optical density. The complete sample-to-answer protocol of our device is fully automated and takes less than 20 min. Overall, the presented microfluidic disc adds to the comparatively small number of fully integrated microfluidic-based platforms that utilize electrochemical detection and exemplifies how electrochemical detection can be enhanced by flow to successfully detect very low levels of biomarkers (e.g. pg mL-1). | - |
dc.identifier.bibliographicCitation | LAB ON A CHIP, v.13, no.18, pp.3747 - 3754 | - |
dc.identifier.doi | 10.1039/c3lc50374g | - |
dc.identifier.issn | 1473-0197 | - |
dc.identifier.scopusid | 2-s2.0-84882239531 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/2689 | - |
dc.identifier.url | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84882239531 | - |
dc.identifier.wosid | 000323111300032 | - |
dc.language | 영어 | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Flow-enhanced electrochemical immunosensors on centrifugal microfluidic platforms | - |
dc.type | Article | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods; Chemistry, Multidisciplinary; Chemistry, Analytical; Nanoscience & Nanotechnology | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology; Chemistry; Science & Technology - Other Topics | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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