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DC Field | Value | Language |
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dc.citation.endPage | 2267 | - |
dc.citation.number | 13 | - |
dc.citation.startPage | 2262 | - |
dc.citation.title | LAB ON A CHIP | - |
dc.citation.volume | 11 | - |
dc.contributor.author | Kim, Tae Hyun | - |
dc.contributor.author | Song, Hyun Seok | - |
dc.contributor.author | Jin, Hye Jun | - |
dc.contributor.author | Lee, Sang Hun | - |
dc.contributor.author | Namgung, Seon | - |
dc.contributor.author | Kim, Un-Kyung | - |
dc.contributor.author | Park, Tai Hyun | - |
dc.contributor.author | Hong, Seunghun | - |
dc.date.accessioned | 2023-12-22T06:07:37Z | - |
dc.date.available | 2023-12-22T06:07:37Z | - |
dc.date.created | 2019-03-04 | - |
dc.date.issued | 2011-07 | - |
dc.description.abstract | We have developed a method to monitor the activities of human taste receptor protein in lipid membrane using carbon nanotube transistors, enabling a "bioelectronic super-taster (BST)", a taste sensor with human-tongue-like selectivity. In this work, human bitter taste receptor protein expressed in E. coli was immobilized on a single-walled carbon nanotube field effect transistor (swCNT-FET) with the lipid membrane. Then, the protein binding activity was monitored using the underlying swCNT-FET, leading to the operation as a BST device. The fabricated BST device could detect bitter tastants at 100 fM concentrations and distinguish between bitter and non-bitter tastants with similar chemical structures just like a human tongue. Furthermore, this strategy was utilized to differentiate the responses of taster or non-taster types of the bitter taste receptor proteins. | - |
dc.identifier.bibliographicCitation | LAB ON A CHIP, v.11, no.13, pp.2262 - 2267 | - |
dc.identifier.doi | 10.1039/c0lc00648c | - |
dc.identifier.issn | 1473-0197 | - |
dc.identifier.scopusid | 2-s2.0-79958811310 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/26265 | - |
dc.identifier.url | https://pubs.rsc.org/en/Content/ArticleLanding/2011/LC/c0lc00648c#!divAbstract | - |
dc.identifier.wosid | 000291555500018 | - |
dc.language | 영어 | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | "Bioelectronic super-taster" device based on taste receptor-carbon nanotube hybrid structures | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods; Chemistry, Multidisciplinary; Chemistry, Analytical; Nanoscience & Nanotechnology | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology; Chemistry; Science & Technology - Other Topics | - |
dc.type.docType | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordPlus | BITTER | - |
dc.subject.keywordPlus | SENSOR | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | BINDING | - |
dc.subject.keywordPlus | SWEET | - |
dc.subject.keywordPlus | PHENYLTHIOCARBAMIDE | - |
dc.subject.keywordPlus | PROTEIN-COUPLED RECEPTORS | - |
dc.subject.keywordPlus | HUMAN OLFACTORY RECEPTOR | - |
dc.subject.keywordPlus | CONDUCTING POLYMERS | - |
dc.subject.keywordPlus | BIOSENSORS | - |
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