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dc.citation.endPage 2359 -
dc.citation.number 16 -
dc.citation.startPage 2356 -
dc.citation.title CHEMICAL COMMUNICATIONS -
dc.citation.volume 55 -
dc.contributor.author Barman, Surajit -
dc.contributor.author Das, Gaurav -
dc.contributor.author Mondal, Prasenjit -
dc.contributor.author Pradhan, Krishnangsu -
dc.contributor.author Jana, Batakrishna -
dc.contributor.author Bhunia, Debmalya -
dc.contributor.author Saha, Abhijit -
dc.contributor.author Kar, Chirantan -
dc.contributor.author Ghosh, Surajit -
dc.date.accessioned 2023-12-21T19:37:37Z -
dc.date.available 2023-12-21T19:37:37Z -
dc.date.created 2019-03-11 -
dc.date.issued 2019-02 -
dc.description.abstract An indole-rich tripodal microtubule inhibitor is designed, which binds at the DCVJ site of tubulin and inhibits its polymerization. It causes apoptotic death of cancer cells without affecting normal cells and inhibits the growth of tumors. Finally, STD-NMR and TR-NOESY experiments reveal that the indole appendages play a crucial role in interacting with tubulin. -
dc.identifier.bibliographicCitation CHEMICAL COMMUNICATIONS, v.55, no.16, pp.2356 - 2359 -
dc.identifier.doi 10.1039/c9cc00074g -
dc.identifier.issn 1359-7345 -
dc.identifier.scopusid 2-s2.0-85061857334 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/26171 -
dc.identifier.url https://pubs.rsc.org/en/Content/ArticleLanding/2019/CC/C9CC00074G#!divAbstract -
dc.identifier.wosid 000459022300023 -
dc.language 영어 -
dc.publisher ROYAL SOC CHEMISTRY -
dc.title Tripodal molecular propellers perturb microtubule dynamics: indole acts as a blade and plays a crucial role in anticancer activity -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.relation.journalWebOfScienceCategory Chemistry, Multidisciplinary -
dc.relation.journalResearchArea Chemistry -
dc.type.docType Article -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.subject.keywordPlus TRIAZINE LIBRARY -
dc.subject.keywordPlus INSIGHTS -
dc.subject.keywordPlus VINBLASTINE -
dc.subject.keywordPlus DISCOVERY -
dc.subject.keywordPlus TUBULIN -
dc.subject.keywordPlus AGENTS -
dc.subject.keywordPlus TARGET -

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