JOURNAL OF FERMENTATION AND BIOENGINEERING, v.74, no.3, pp.185 - 188
Abstract
Due to the reduced growth rate, plasmid-haboring cells give smaller colonies on agar plates than their plasmid-free counterparts. Based on the difference in colony size, a new method to measure plasmid stability is proposed. The new method is flexible, fast, and agrees well with the replica plating method.