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DC Field | Value | Language |
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dc.citation.endPage | 1961 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1949 | - |
dc.citation.title | MAGNETIC RESONANCE IN MEDICINE | - |
dc.citation.volume | 80 | - |
dc.contributor.author | Lee, DongKyu | - |
dc.contributor.author | Song, Young Kyu | - |
dc.contributor.author | Park, Bumwoo | - |
dc.contributor.author | Cho, Hwapyeong | - |
dc.contributor.author | Yeom, Jinsup | - |
dc.contributor.author | Cho, Gyunggoo | - |
dc.contributor.author | Cho, Hyungjoon | - |
dc.date.accessioned | 2023-12-21T20:07:44Z | - |
dc.date.available | 2023-12-21T20:07:44Z | - |
dc.date.created | 2018-04-03 | - |
dc.date.issued | 2018-11 | - |
dc.description.abstract | Purpose: To evaluate the robustness of MR transverse relaxation times of trabecular bone from spin-echo and gradient-echo acquisitions at multiple spatial resolutions of 7 T. Methods: The effects of MRI resolutions to T-2 and T-2* trabecular bone were numerically evaluated by Monte Carlo simulations. T-2, T-2* and trabecular structural indices from multislice multi-echo and UTE acquisitions were measured in defatted human distal femoral condyles on a 7 T scanner. Reference structural indices were extracted from high-resolution microcomputed tomography images. For bovine knee trabecular samples with intact bone marrow, T-2 and T-2* were measured by degrading spatial resolutions on a 7 T system. Results: In the defatted trabecular experiment, both T-2 and T-2* values showed strong (vertical bar r vertical bar> 0.80) correlations with trabecular spacing and number, at a high spatial resolution of 125 mu m(3). The correlations for MR image-segmentation-olutions of 250 and 500 mu m(3). The correlations for T-2* rapidly dropped (vertical bar r vertical bar< 0.50) at a spatial resolution of 500 mu m(3), whereas those for T-2* remained consistently high (vertical bar r vertical bar> 0.85). In the bovine trabecular experiments with intact marrow, low- resolution (approximately 1 mm(3), 2 minutes) T-2 values did not shorten (vertical bar r vertical bar> 0.95 with respect to approximately 0.4mm(3), 11 minutes) and maintained consistent correlations (vertical bar r vertical bar > 0.70) with respect to trabecular spacing (turbo spin echo, 22.5 minutes). Conclusion: T-2 measurements of trabeculae at 7 T are robust with degrading spatial resolution and may be preferable in assessing trabecular spacing index with reduced scan time, when high-resolution 3D micro-MRI is difficult to obtain. |
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dc.identifier.bibliographicCitation | MAGNETIC RESONANCE IN MEDICINE, v.80, no.5, pp.1949 - 1961 | - |
dc.identifier.doi | 10.1002/mrm.27202 | - |
dc.identifier.issn | 0740-3194 | - |
dc.identifier.scopusid | 2-s2.0-85045415553 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/23958 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/abs/10.1002/mrm.27202 | - |
dc.identifier.wosid | 000448872700016 | - |
dc.language | 영어 | - |
dc.publisher | WILEY-BLACKWELL | - |
dc.title | The robustness of T2 value as a trabecular structural index at multiple spatial resolutions of 7 Tesla MRI | - |
dc.type | Article | - |
dc.description.isOpenAccess | FALSE | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | magnetic resonance relaxations | - |
dc.subject.keywordAuthor | magnetic resonance spatial resolution | - |
dc.subject.keywordAuthor | trabecular structure | - |
dc.subject.keywordPlus | ARTICULAR-CARTILAGE | - |
dc.subject.keywordPlus | BONE-STRUCTURE | - |
dc.subject.keywordPlus | MAGNETIC-FIELD | - |
dc.subject.keywordPlus | 3 T | - |
dc.subject.keywordPlus | OSTEOPOROSIS | - |
dc.subject.keywordPlus | INTERRELATIONSHIP | - |
dc.subject.keywordPlus | MICROARCHITECTURE | - |
dc.subject.keywordPlus | INTERFEROMETRY | - |
dc.subject.keywordPlus | RELAXATION | - |
dc.subject.keywordPlus | PARAMETERS | - |
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