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Cho, Hyungjoon
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dc.citation.endPage 1961 -
dc.citation.number 5 -
dc.citation.startPage 1949 -
dc.citation.volume 80 - Lee, DongKyu - Song, Young Kyu - Park, Bumwoo - Cho, Hwapyeong - Yeom, Jinsup - Cho, Gyunggoo - Cho, Hyungjoon - 2023-12-21T20:07:44Z - 2023-12-21T20:07:44Z - 2018-04-03 - 2018-11 -
dc.description.abstract Purpose: To evaluate the robustness of MR transverse relaxation times of trabecular bone from spin-echo and gradient-echo acquisitions at multiple spatial resolutions of 7 T.

Methods: The effects of MRI resolutions to T-2 and T-2* trabecular bone were numerically evaluated by Monte Carlo simulations. T-2, T-2* and trabecular structural indices from multislice multi-echo and UTE acquisitions were measured in defatted human distal femoral condyles on a 7 T scanner. Reference structural indices were extracted from high-resolution microcomputed tomography images. For bovine knee trabecular samples with intact bone marrow, T-2 and T-2* were measured by degrading spatial resolutions on a 7 T system.

Results: In the defatted trabecular experiment, both T-2 and T-2* values showed strong (vertical bar r vertical bar> 0.80) correlations with trabecular spacing and number, at a high spatial resolution of 125 mu m(3). The correlations for MR image-segmentation-olutions of 250 and 500 mu m(3). The correlations for T-2* rapidly dropped (vertical bar r vertical bar< 0.50) at a spatial resolution of 500 mu m(3), whereas those for T-2* remained consistently high (vertical bar r vertical bar> 0.85). In the bovine trabecular experiments with intact marrow, low- resolution (approximately 1 mm(3), 2 minutes) T-2 values did not shorten (vertical bar r vertical bar> 0.95 with respect to approximately 0.4mm(3), 11 minutes) and maintained consistent correlations (vertical bar r vertical bar > 0.70) with respect to trabecular spacing (turbo spin echo, 22.5 minutes).

Conclusion: T-2 measurements of trabeculae at 7 T are robust with degrading spatial resolution and may be preferable in assessing trabecular spacing index with reduced scan time, when high-resolution 3D micro-MRI is difficult to obtain.
dc.identifier.bibliographicCitation MAGNETIC RESONANCE IN MEDICINE, v.80, no.5, pp.1949 - 1961 -
dc.identifier.doi 10.1002/mrm.27202 -
dc.identifier.issn 0740-3194 -
dc.identifier.scopusid 2-s2.0-85045415553 -
dc.identifier.uri -
dc.identifier.url -
dc.identifier.wosid 000448872700016 -
dc.language 영어 -
dc.publisher WILEY-BLACKWELL -
dc.title The robustness of T2 value as a trabecular structural index at multiple spatial resolutions of 7 Tesla MRI -
dc.type Article -
dc.description.isOpenAccess FALSE -
dc.relation.journalWebOfScienceCategory Radiology, Nuclear Medicine & Medical Imaging -
dc.relation.journalResearchArea Radiology, Nuclear Medicine & Medical Imaging -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -
dc.subject.keywordAuthor magnetic resonance relaxations -
dc.subject.keywordAuthor magnetic resonance spatial resolution -
dc.subject.keywordAuthor trabecular structure -
dc.subject.keywordPlus ARTICULAR-CARTILAGE -
dc.subject.keywordPlus BONE-STRUCTURE -
dc.subject.keywordPlus MAGNETIC-FIELD -
dc.subject.keywordPlus 3 T -
dc.subject.keywordPlus OSTEOPOROSIS -
dc.subject.keywordPlus INTERRELATIONSHIP -
dc.subject.keywordPlus MICROARCHITECTURE -
dc.subject.keywordPlus INTERFEROMETRY -
dc.subject.keywordPlus RELAXATION -
dc.subject.keywordPlus PARAMETERS -


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