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DC Field | Value | Language |
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dc.citation.endPage | 3655 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 3649 | - |
dc.citation.title | ACS NANO | - |
dc.citation.volume | 3 | - |
dc.contributor.author | Lo, Young-Seop | - |
dc.contributor.author | Nam, Dong Hyun | - |
dc.contributor.author | So, Hye-Mi | - |
dc.contributor.author | Chang, Hyunju | - |
dc.contributor.author | Kim, Ju-Jin | - |
dc.contributor.author | Kim, Yong Hwan | - |
dc.contributor.author | Lee, Jeong-O | - |
dc.date.accessioned | 2023-12-22T07:37:50Z | - |
dc.date.available | 2023-12-22T07:37:50Z | - |
dc.date.created | 2016-09-06 | - |
dc.date.issued | 2009-11 | - |
dc.description.abstract | We herein demonstrate that Ni-decorated single-walled carbon nanotube field effect transistors (SWNT-FETs) combined with antibody fragments can be used as effective biosensing platforms. Nanoscales Ni particles 20 to 60 nm in diameter were formed on the sidewalls of SWNT-FETs using an electrochemical method. Carcinoembryonic antigen (CEA)-binding single chain variable fragments (scFvs) with a hexahistidine tag [(his)](6)] were synthesized using genetic engineering, and ordered immobilization of anti-CEA ScFvs on Ni nanoparticles was achieved by exploiting the specific interaction between hexahistidine and Ni. Whereas randomly oriented anti(EA scFvs did not impart a noticeable change of conductance upon addition of CEA, a clear increase in conductance was observed using Ni-decorated SWNT-FETs functionalized with engineered scFvs | - |
dc.identifier.bibliographicCitation | ACS NANO, v.3, no.11, pp.3649 - 3655 | - |
dc.identifier.doi | 10.1021/nn900540a | - |
dc.identifier.issn | 1936-0851 | - |
dc.identifier.scopusid | 2-s2.0-73249153396 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/20383 | - |
dc.identifier.url | http://pubs.acs.org/doi/abs/10.1021/nn900540a | - |
dc.identifier.wosid | 000271951200041 | - |
dc.language | 영어 | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Oriented Immobilization of Antibody Fragments on Ni-Decorated Single-Walled Carbon Nanotube Devices | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
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