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강주헌

Kang, Joo H.
Translational Multiscale Biofluidics Lab.
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dc.citation.endPage 3217 -
dc.citation.number 6 -
dc.citation.startPage 3213 -
dc.citation.title NANO LETTERS -
dc.citation.volume 12 -
dc.contributor.author Kanapathipillai, Mathumai -
dc.contributor.author Mammoto, Akiko -
dc.contributor.author Mammoto, Tadanori -
dc.contributor.author Kang, Joo H. -
dc.contributor.author Jiang, Elisabeth -
dc.contributor.author Ghosh, Kaustabh -
dc.contributor.author Korin, Netanel -
dc.contributor.author Gibbs, Ashley -
dc.contributor.author Mannix, Robert -
dc.contributor.author Ingber, Donald E. -
dc.date.accessioned 2023-12-22T05:09:14Z -
dc.date.available 2023-12-22T05:09:14Z -
dc.date.created 2016-06-03 -
dc.date.issued 2012-05 -
dc.description.abstract A cancer nanotherapeutic has been developed that targets the extracellular matrix (ECM)-modifying enzyme lysyl oxidase (LOX) and alters the ECM structure. Poly(D,L-lactide-co-glycolide) nanoparticles (similar to 220 nm) coated with a LOX inhibitory antibody bind to ECM and suppress mammary cancer cell growth and invasion in vitro as well as tumor expansion in vivo, with greater efficiency than soluble anti-LOX antibody. This nanomaterials approach opens a new path for treating cancer with higher efficacy and decreased side effects. -
dc.identifier.bibliographicCitation NANO LETTERS, v.12, no.6, pp.3213 - 3217 -
dc.identifier.doi 10.1021/nl301206p -
dc.identifier.issn 1530-6984 -
dc.identifier.scopusid 2-s2.0-84862301989 -
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/19506 -
dc.identifier.url http://pubs.acs.org/doi/abs/10.1021/nl301206p -
dc.identifier.wosid 000305106400093 -
dc.language 영어 -
dc.publisher AMER CHEMICAL SOC -
dc.title Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix -
dc.type Article -
dc.description.journalRegisteredClass scie -
dc.description.journalRegisteredClass scopus -

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