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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 3217 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 3213 | - |
dc.citation.title | NANO LETTERS | - |
dc.citation.volume | 12 | - |
dc.contributor.author | Kanapathipillai, Mathumai | - |
dc.contributor.author | Mammoto, Akiko | - |
dc.contributor.author | Mammoto, Tadanori | - |
dc.contributor.author | Kang, Joo H. | - |
dc.contributor.author | Jiang, Elisabeth | - |
dc.contributor.author | Ghosh, Kaustabh | - |
dc.contributor.author | Korin, Netanel | - |
dc.contributor.author | Gibbs, Ashley | - |
dc.contributor.author | Mannix, Robert | - |
dc.contributor.author | Ingber, Donald E. | - |
dc.date.accessioned | 2023-12-22T05:09:14Z | - |
dc.date.available | 2023-12-22T05:09:14Z | - |
dc.date.created | 2016-06-03 | - |
dc.date.issued | 2012-05 | - |
dc.description.abstract | A cancer nanotherapeutic has been developed that targets the extracellular matrix (ECM)-modifying enzyme lysyl oxidase (LOX) and alters the ECM structure. Poly(D,L-lactide-co-glycolide) nanoparticles (similar to 220 nm) coated with a LOX inhibitory antibody bind to ECM and suppress mammary cancer cell growth and invasion in vitro as well as tumor expansion in vivo, with greater efficiency than soluble anti-LOX antibody. This nanomaterials approach opens a new path for treating cancer with higher efficacy and decreased side effects. | - |
dc.identifier.bibliographicCitation | NANO LETTERS, v.12, no.6, pp.3213 - 3217 | - |
dc.identifier.doi | 10.1021/nl301206p | - |
dc.identifier.issn | 1530-6984 | - |
dc.identifier.scopusid | 2-s2.0-84862301989 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/19506 | - |
dc.identifier.url | http://pubs.acs.org/doi/abs/10.1021/nl301206p | - |
dc.identifier.wosid | 000305106400093 | - |
dc.language | 영어 | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Inhibition of mammary tumor growth using lysyl oxidase-targeting nanoparticles to modify extracellular matrix | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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