Full metadata record
DC Field | Value | Language |
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dc.citation.startPage | 215 | - |
dc.citation.title | GENOME BIOLOGY | - |
dc.citation.volume | 16 | - |
dc.contributor.author | Chung, Oksung | - |
dc.contributor.author | Jin, Seondeok | - |
dc.contributor.author | Cho, Yun Sung | - |
dc.contributor.author | Lim, Jeongheui | - |
dc.contributor.author | Kim, Hyunho | - |
dc.contributor.author | Jho, Sungwoong | - |
dc.contributor.author | Kim, Hak-Min | - |
dc.contributor.author | Jun, JeHoon | - |
dc.contributor.author | Lee, HyeJin | - |
dc.contributor.author | Chon, Alvin | - |
dc.contributor.author | Ko, Junsu | - |
dc.contributor.author | Edwards, Jeremy | - |
dc.contributor.author | Weber, Jessica A. | - |
dc.contributor.author | Han, Kyudong | - |
dc.contributor.author | O'Brien, Stephen J. | - |
dc.contributor.author | Manica, Andrea | - |
dc.contributor.author | Bhak, Jong Hwa | - |
dc.contributor.author | Paek, Woon Kee | - |
dc.date.accessioned | 2023-12-22T00:39:47Z | - |
dc.date.available | 2023-12-22T00:39:47Z | - |
dc.date.created | 2015-11-20 | - |
dc.date.issued | 2015-10 | - |
dc.description.abstract | Background: The cinereous vulture, Aegypius monachus, is the largest bird of prey and plays a key role in the ecosystem by removing carcasses, thus preventing the spread of diseases. Its feeding habits force it to cope with constant exposure to pathogens, making this species an interesting target for discovering functionally selected genetic variants. Furthermore, the presence of two independently evolved vulture groups, Old World and New World vultures, provides a natural experiment in which to investigate convergent evolution due to obligate scavenging. Results: We sequenced the genome of a cinereous vulture, and mapped it to the bald eagle reference genome, a close relative with a divergence time of 18 million years. By comparing the cinereous vulture to other avian genomes, we find positively selected genetic variations in this species associated with respiration, likely linked to their ability of immune defense responses and gastric acid secretion, consistent with their ability to digest carcasses. Comparisons between the Old World and New World vulture groups suggest convergent gene evolution. We assemble the cinereous vulture blood transcriptome from a second individual, and annotate genes. Finally, we infer the demographic history of the cinereous vulture which shows marked fluctuations in effective population size during the late Pleistocene. Conclusions: We present the first genome and transcriptome analyses of the cinereous vulture compared to other avian genomes and transcriptomes, revealing genetic signatures of dietary and environmental adaptations accompanied by possible convergent evolution between the Old World and New World vultures | - |
dc.identifier.bibliographicCitation | GENOME BIOLOGY, v.16, pp.215 | - |
dc.identifier.doi | 10.1186/s13059-015-0780-4 | - |
dc.identifier.issn | 1474-760X | - |
dc.identifier.scopusid | 2-s2.0-84945175181 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/17822 | - |
dc.identifier.url | http://www.genomebiology.com/2015/16/1/215 | - |
dc.identifier.wosid | 000363097200001 | - |
dc.language | 영어 | - |
dc.publisher | BIOMED CENTRAL LTD | - |
dc.title | The first whole genome and transcriptome of the cinereous vulture reveals adaptation in the gastric and immune defense systems and possible convergent evolution between the Old and New World vultures | - |
dc.type | Article | - |
dc.description.isOpenAccess | TRUE | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology; Genetics & Heredity | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology; Genetics & Heredity | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.subject.keywordAuthor | Cinereous vulture | - |
dc.subject.keywordAuthor | Old world vulture | - |
dc.subject.keywordAuthor | New world vulture | - |
dc.subject.keywordAuthor | Transcriptome | - |
dc.subject.keywordAuthor | Genome | - |
dc.subject.keywordAuthor | Next-generation sequencing | - |
dc.subject.keywordPlus | RNA-SEQ DATA | - |
dc.subject.keywordPlus | DIFFERENTIAL EXPRESSION ANALYSIS | - |
dc.subject.keywordPlus | KAPPA-B ACTIVATION | - |
dc.subject.keywordPlus | SWISS-MODEL | - |
dc.subject.keywordPlus | GYPS-FULVUS | - |
dc.subject.keywordPlus | GENE | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.subject.keywordPlus | SEQUENCES | - |
dc.subject.keywordPlus | ALIGNMENT | - |
dc.subject.keywordPlus | SERVER | - |
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