There are no files associated with this item.
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 176 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 170 | - |
dc.citation.title | ANNALS OF NUTRITION AND METABOLISM | - |
dc.citation.volume | 44 | - |
dc.contributor.author | Jeon, SM | - |
dc.contributor.author | Kim, HS | - |
dc.contributor.author | Lee, TG | - |
dc.contributor.author | Ryu, SH | - |
dc.contributor.author | Suh, PG | - |
dc.contributor.author | Byun, SJ | - |
dc.contributor.author | Park, YB | - |
dc.contributor.author | Choi, MS | - |
dc.date.accessioned | 2023-12-22T12:07:19Z | - |
dc.date.available | 2023-12-22T12:07:19Z | - |
dc.date.created | 2015-08-19 | - |
dc.date.issued | 2000-07 | - |
dc.description.abstract | Areca catechu L. extracts I and II, prepared using two different solvent systems, exhibited strong inhibitory activities against pancreatic cholesterol esterase (pCEase) in vitro. To determine their cholesterol-towering effects, these two extracts were investigated by analyzing plasma lipid levels, intestinal enzyme activities, and the absorption of cholesteryl oleate. For 6 days, male rats were fed a diet containing cholesteryl oleate (0.5 g/100 g of body weight) either with or without the Areca nut extract supplements. The supplementation of the two Areca nut extracts significantly lowered the concentrations of plasma cholesterol by 13.4 and 11.7% and plasma triglycerides by 35.0 and 36.9%, respectively, compared with the pre-experimental values. However, when the cholesteryl oleate diet was fed without any Areca nut extract in high-cholesterol control, the plasma cholesterol and triglyceride concentrations significantly increased by 13.6 and 15.9%, respectively, compared with the preexperimental va lues. After 6 days of treatment, the intestinal pCEase activities were significantly lower in the groups supplemented with the Areca nut extracts (37.8 and 26.5%) than in the group with no extract supplement (83.2%). The supplements also significantly elevated the excretion of [1,2(n)-H-3]cholesteryl oleate administered orally, when determined by the large intestinal contents, 930.5 Bq/day (Areca I) and 1,766.3 Bq/day (Areca II) vs. 98.1 Bq/day (high-cholesteryl oleate (CO) control). The inhibition of pCEase activity with the supplementation of the Areca nut extracts could account for the decrease in [1,2(n)-H-3]cholesteryl oleate absorption that resulted in decreased radioactivity in blood. Copyright (C) 2000 S. Karger AG, Basel | - |
dc.identifier.bibliographicCitation | ANNALS OF NUTRITION AND METABOLISM, v.44, no.4, pp.170 - 176 | - |
dc.identifier.doi | 10.1159/000012841 | - |
dc.identifier.issn | 0250-6807 | - |
dc.identifier.scopusid | 2-s2.0-0033662680 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/16480 | - |
dc.identifier.url | http://www.karger.com/Article/Abstract/12841 | - |
dc.identifier.wosid | 000165864900006 | - |
dc.language | 영어 | - |
dc.publisher | KARGER | - |
dc.title | Lower absorption of cholesteryl oleate in rats supplemented with Areca catechu L. extract | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Tel : 052-217-1404 / Email : scholarworks@unist.ac.kr
Copyright (c) 2023 by UNIST LIBRARY. All rights reserved.
ScholarWorks@UNIST was established as an OAK Project for the National Library of Korea.