Detailed Information
Cited time in 
Cited time in 
Cited time in
Metadata Downloads
Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.citation.endPage | 109 | - |
| dc.citation.number | 3 | - |
| dc.citation.startPage | 101 | - |
| dc.citation.title | EXPERIMENTAL AND MOLECULAR MEDICINE | - |
| dc.citation.volume | 32 | - |
| dc.contributor.author | Kim, Myung Jong | - |
| dc.contributor.author | Kim, Euikyung | - |
| dc.contributor.author | Ryu, Sung Ho | - |
| dc.contributor.author | Suh, Pann-Ghill | - |
| dc.date.accessioned | 2023-12-22T12:06:52Z | - |
| dc.date.available | 2023-12-22T12:06:52Z | - |
| dc.date.created | 2015-08-19 | - |
| dc.date.issued | 2000-09 | - |
| dc.description.abstract | Phospholipase C (PLC)(1) hydrolyzes phosphatidylinositol 4,5-bisphosphate to generate the second messengers, inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). IP3 induces a transient increase in intracellular free Ca2+, while DAG directly activates protein kinase C. Upon stimulation of cells with growth factors, PLC-gamma 1 is activated upon their association with and phosphorylation by receptor and non-receptor tyrosine kinases. In this review, we will focus on the activation mechanism and regulatory function of PLC-gamma 1 | - |
| dc.identifier.bibliographicCitation | EXPERIMENTAL AND MOLECULAR MEDICINE, v.32, no.3, pp.101 - 109 | - |
| dc.identifier.doi | 10.1038/emm.2000.18 | - |
| dc.identifier.issn | 1226-3613 | - |
| dc.identifier.scopusid | 2-s2.0-0034734605 | - |
| dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/16478 | - |
| dc.identifier.url | http://www.nature.com/emm/journal/v32/n3/abs/emm200018a.html | - |
| dc.identifier.wosid | 000089869500001 | - |
| dc.language | 영어 | - |
| dc.publisher | KOREAN SOC MED BIOCHEMISTRY MOLECULAR BIOLOGY | - |
| dc.title | The mechanism of phospholipase C-gamma 1 regulation | - |
| dc.type | Article | - |
| dc.description.isOpenAccess | FALSE | - |
| dc.description.journalRegisteredClass | scopus | - |
Items in Repository are protected by copyright, with all rights reserved, unless otherwise indicated.