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Suh, Pann-Ghill
BioSignal Network Lab (BSN)
Research Interests
  • Signal transduction, cancer, metabolism, phospholipase C

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REDUCED EXPRESSION OF PLC-GAMMA DURING THE DIFFERENTIATION OF MOUSE F9 TERATOCARCINOMA CELLS

DC Field Value Language
dc.contributor.author Lee, Young-Han ko
dc.contributor.author Lee, Ho-Young ko
dc.contributor.author Ryu, Sung Ho ko
dc.contributor.author Suh, Pann-Ghill ko
dc.contributor.author Kim, Kyu-Won ko
dc.date.available 2015-09-01T07:25:27Z -
dc.date.created 2015-08-20 ko
dc.date.issued 1993-02 -
dc.identifier.citation CANCER LETTERS, v.68, no.2-3, pp.237 - 242 ko
dc.identifier.issn 0304-3835 ko
dc.identifier.uri https://scholarworks.unist.ac.kr/handle/201301/16460 -
dc.identifier.uri http://www.sciencedirect.com/science/article/pii/030438359390152Y ko
dc.description.abstract Expression of phosphoinositide-specific phospholipase C (PLC)-gamma during the retinoic acid(RA)-induced differentiation of F9 teratocarcinoma stem cells was investigated. PLC-gamma activity and PLC-gamma protein content were decreased during the differentiation of F9 teratocarcinoma stem cells induced by a combination (RACt) of RA, dibutyryl cyclic AMP (C) and theophylline (T). However, PLC-gamma activity and protein levels in RA- or C- and T-treated F9 cells remained the same as that of the F9 stem cells. Northern analysis of the 5.4-kb PLC-gamma transcript in differentiated F9 cells by RACT revealed that RACT decreased the PLC-gamma gene expression. These results suggest that the expression of PLC-gamma is negatively controlled by RACT treatment in the differentiation of F9 teratocarcinoma stem cells ko
dc.description.statementofresponsibility close -
dc.language ENG ko
dc.publisher ELSEVIER IRELAND LTD ko
dc.subject differentiation ko
dc.subject F9 teratocarcinoma ko
dc.subject phospholipase C-γ ko
dc.title REDUCED EXPRESSION OF PLC-GAMMA DURING THE DIFFERENTIATION OF MOUSE F9 TERATOCARCINOMA CELLS ko
dc.type ARTICLE ko
dc.identifier.scopusid 2-s2.0-0027460481 ko
dc.identifier.wosid A1993KQ38000020 ko
dc.type.rims ART ko
dc.description.wostc 7 *
dc.description.scopustc 5 *
dc.date.tcdate 2015-12-28 *
dc.date.scptcdate 2015-11-04 *
dc.identifier.doi 10.1016/0304-3835(93)90152-Y ko
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