dc.citation.endPage |
242 |
- |
dc.citation.number |
2-3 |
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dc.citation.startPage |
237 |
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dc.citation.title |
CANCER LETTERS |
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dc.citation.volume |
68 |
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dc.contributor.author |
Lee, Young-Han |
- |
dc.contributor.author |
Lee, Ho-Young |
- |
dc.contributor.author |
Ryu, Sung Ho |
- |
dc.contributor.author |
Suh, Pann-Ghill |
- |
dc.contributor.author |
Kim, Kyu-Won |
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dc.date.accessioned |
2023-12-22T13:06:48Z |
- |
dc.date.available |
2023-12-22T13:06:48Z |
- |
dc.date.created |
2015-08-20 |
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dc.date.issued |
1993-02 |
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dc.description.abstract |
Expression of phosphoinositide-specific phospholipase C (PLC)-gamma during the retinoic acid(RA)-induced differentiation of F9 teratocarcinoma stem cells was investigated. PLC-gamma activity and PLC-gamma protein content were decreased during the differentiation of F9 teratocarcinoma stem cells induced by a combination (RACt) of RA, dibutyryl cyclic AMP (C) and theophylline (T). However, PLC-gamma activity and protein levels in RA- or C- and T-treated F9 cells remained the same as that of the F9 stem cells. Northern analysis of the 5.4-kb PLC-gamma transcript in differentiated F9 cells by RACT revealed that RACT decreased the PLC-gamma gene expression. These results suggest that the expression of PLC-gamma is negatively controlled by RACT treatment in the differentiation of F9 teratocarcinoma stem cells |
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dc.identifier.bibliographicCitation |
CANCER LETTERS, v.68, no.2-3, pp.237 - 242 |
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dc.identifier.doi |
10.1016/0304-3835(93)90152-Y |
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dc.identifier.issn |
0304-3835 |
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dc.identifier.scopusid |
2-s2.0-0027460481 |
- |
dc.identifier.uri |
https://scholarworks.unist.ac.kr/handle/201301/16460 |
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dc.identifier.url |
http://www.sciencedirect.com/science/article/pii/030438359390152Y |
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dc.identifier.wosid |
A1993KQ38000020 |
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dc.language |
영어 |
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dc.publisher |
ELSEVIER IRELAND LTD |
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dc.title |
REDUCED EXPRESSION OF PLC-GAMMA DURING THE DIFFERENTIATION OF MOUSE F9 TERATOCARCINOMA CELLS |
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dc.type |
Article |
- |
dc.description.journalRegisteredClass |
scopus |
- |