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DC Field | Value | Language |
---|---|---|
dc.citation.endPage | 242 | - |
dc.citation.number | 2-3 | - |
dc.citation.startPage | 237 | - |
dc.citation.title | CANCER LETTERS | - |
dc.citation.volume | 68 | - |
dc.contributor.author | Lee, Young-Han | - |
dc.contributor.author | Lee, Ho-Young | - |
dc.contributor.author | Ryu, Sung Ho | - |
dc.contributor.author | Suh, Pann-Ghill | - |
dc.contributor.author | Kim, Kyu-Won | - |
dc.date.accessioned | 2023-12-22T13:06:48Z | - |
dc.date.available | 2023-12-22T13:06:48Z | - |
dc.date.created | 2015-08-20 | - |
dc.date.issued | 1993-02 | - |
dc.description.abstract | Expression of phosphoinositide-specific phospholipase C (PLC)-gamma during the retinoic acid(RA)-induced differentiation of F9 teratocarcinoma stem cells was investigated. PLC-gamma activity and PLC-gamma protein content were decreased during the differentiation of F9 teratocarcinoma stem cells induced by a combination (RACt) of RA, dibutyryl cyclic AMP (C) and theophylline (T). However, PLC-gamma activity and protein levels in RA- or C- and T-treated F9 cells remained the same as that of the F9 stem cells. Northern analysis of the 5.4-kb PLC-gamma transcript in differentiated F9 cells by RACT revealed that RACT decreased the PLC-gamma gene expression. These results suggest that the expression of PLC-gamma is negatively controlled by RACT treatment in the differentiation of F9 teratocarcinoma stem cells | - |
dc.identifier.bibliographicCitation | CANCER LETTERS, v.68, no.2-3, pp.237 - 242 | - |
dc.identifier.doi | 10.1016/0304-3835(93)90152-Y | - |
dc.identifier.issn | 0304-3835 | - |
dc.identifier.scopusid | 2-s2.0-0027460481 | - |
dc.identifier.uri | https://scholarworks.unist.ac.kr/handle/201301/16460 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/030438359390152Y | - |
dc.identifier.wosid | A1993KQ38000020 | - |
dc.language | 영어 | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.title | REDUCED EXPRESSION OF PLC-GAMMA DURING THE DIFFERENTIATION OF MOUSE F9 TERATOCARCINOMA CELLS | - |
dc.type | Article | - |
dc.description.journalRegisteredClass | scopus | - |
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